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Record W4311778562 · doi:10.1016/j.ceja.2022.100435

Transformation by plasma technology of cisplatin found in hospital's wastewaters into platinum-containing nanoparticles

2022· article· en· W4311778562 on OpenAlex

Why this work is in the frame

A frame that forgets how it found something cannot be audited. These are the routes that admitted this work.

affAt least one author lists a Canadian institution in the pinned OpenAlex snapshot.
fundA Canadian funder is recorded on the work.

Bibliographic record

VenueChemical Engineering Journal Advances · 2022
Typearticle
Languageen
FieldMedicine
TopicPlasma Applications and Diagnostics
Canadian institutionsUniversité LavalCentre hospitalier universitaire de Québec
FundersNatural Resources CanadaNatural Sciences and Engineering Research Council of Canada
KeywordsCisplatinPlatinumDielectric barrier dischargeChemistryWastewaterNanoparticleX-ray photoelectron spectroscopyPlatinum nanoparticlesAtmospheric pressureAtmospheric-pressure plasmaChemical engineeringPlasmaNuclear chemistryMaterials scienceNanotechnologyOrganic chemistryEnvironmental engineeringCatalysisEnvironmental scienceSurgeryMedicineChemotherapy

Abstract

fetched live from OpenAlex

Platinum-containing molecules such as cisplatin figure among oncology's most widely used antineoplastic agents. Cisplatin excreted in the urine usually ends up in municipal wastewater, with a strong toxicological and carcinogenic impact on the environment. Thus, cisplatin should be inactivated before reaching wastewater to attenuate its environmental impact. However, conventional recommended procedures use large quantities of toxic acids, which are not sustainable processes. In this study, a dielectric barrier discharge (DBD) atmospheric pressure plasma reactor is used to degrade cisplatin in wastewater, allowing platinum's recuperation. The article describes the plasma discharge (power, electron temperature, and density) and confirms the most stable operation parameters under Ar and Ar+H2 discharges. Cisplatin is diluted in water or synthetic urine, and plasma treatment is conducted for 30 min. The process degrades cisplatin molecules by conversion into platinum-rich nanoparticles (NPs). These nanoparticles are efficiently recuperated by centrifugation and are characterized by transmission electron microscopy and X-ray photoelectron spectroscopy (XPS). The mass-balance assessment confirms that more than 90% of cisplatin is degraded and recuperated as Pt-rich NPs.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Bench or experimental · Consensus signal: Bench or experimental
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.017
Threshold uncertainty score0.361

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.003
GPT teacher head0.215
Teacher spread0.211 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it