CHARACTERIZATION OF BACTEREMIC AND NON-BACTEREMIC SYNDROMES OF INVASIVE ESCHERICHIA COLI DISEASE AMONG HOSPITALIZED ADULTS AGED ≥60 YEARS: FINDINGS FROM A PROSPECTIVE, MULTINATIONAL, OBSERVATIONAL STUDY (EXPECT-2)
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Bibliographic record
Abstract
losis occurs in less than 5% of cases.Aim.To demonstrate a clinical case of neurobrucellosis associated with difficulties in diagnostics in Rostov-on-Don, where neurobrucellosis was not recorded within 30 years.Methods: Case of neurobrucellosis in 30-year-old patient hospitalized in the infectious diseases hospital in .Rostov-on-Don with acute serous meningitis of unspecified etiology.Findings: Patient was resident of Dagestan, where he was engaged in sheep breeding.The disease started with fever, headache.Patient was hospitalized in the district hospital in the Rostov region, where negative Wright agglutination test on brucellosis was received.After the course of antibacterial therapy his condition was improved: fever and headache disappeared and patient was discharged.However, after 10 days, the temperature rose again to 39 0C, headache, nausea, vomiting appeared, lethargy, sensory aphasia developed.The patient was hospitalized in the neurological department.After exclusion of acute cerebrovascular accident, he was transferred to an infectious regional hospital in Rostov-on-Don.Cerebrospinal fluid (CSF) analysis: cytosis -760 cells/mm3 (lymphocytes 98%,), RT-PCR on DNA of Brucella spp. in CSF positive.The patient's condition periodically worsened: disorientation, psychomotor agitation appeared.The patient received dehydration therapy, combined antibacterial therapy (rifampicin + doxycycline + ceftriaxone), during 6 weeks treatment the progression of neurological deficit stopped, clinical improvement occurred.Discussion: The case demonstrate difficulties in diagnostic of neurobrucellosis, which in 50% of cases begins with diffuse encephalopathy and meningoencephalitis, various degenerative lesions of the nervous system that occur not only in the acute stage of the disease, but also in chronic forms.Conclusion: This case is interesting for clinicians due to rare occurrence of neurobrucellosis in clinical practice.
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Full frame distilled prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.
Codex and Gemma teacher scores by category
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.000 | 0.001 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.000 | 0.000 |
| Bibliometrics | 0.001 | 0.000 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.000 | 0.000 |
| Insufficient payload (model declined to judge) | 0.000 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it