ESICM guidelines on acute respiratory distress syndrome: definition, phenotyping and respiratory support strategies
Why is this work in the frame?
A frame that forgets how it found something cannot be audited. These are the routes that admitted this work.
Full frame distilled prediction
Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.
- Candidate categories
- Meta-epidemiology (narrow)
- Consensus categories
- none
- Domain
- Candidate signal: noneConsensus signal: none
- Study design
- Candidate signal: Not applicableConsensus signal: Not applicable
- Genre
- Candidate signal: EmpiricalConsensus signal: Empirical
- Teacher disagreement score
- 0.270
- Threshold uncertainty score
- 1.000
- Validation status
machine_predicted_unvalidated·codex-gemma-dda1882f352a
Codex and Gemma teacher scores by category
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.001 | 0.002 |
| Meta-epidemiology (narrow) | 0.001 | 0.000 |
| Meta-epidemiology (broad) | 0.001 | 0.000 |
| Bibliometrics | 0.001 | 0.001 |
| Science and technology studies | 0.000 | 0.001 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.000 | 0.000 |
| Insufficient payload (model declined to judge) | 0.000 | 0.000 |
Machine scores (provisional)
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
- Teacher spread
- 0.261 · how far apart the two teachers sit on this one work
- Validation status
score_only:v0-immature-baseline· verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it
Abstract
The aim of these guidelines is to update the 2017 clinical practice guideline (CPG) of the European Society of Intensive Care Medicine (ESICM). The scope of this CPG is limited to adult patients and to non-pharmacological respiratory support strategies across different aspects of acute respiratory distress syndrome (ARDS), including ARDS due to coronavirus disease 2019 (COVID-19). These guidelines were formulated by an international panel of clinical experts, one methodologist and patients' representatives on behalf of the ESICM. The review was conducted in compliance with the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) statement recommendations. We followed the Grading of Recommendations Assessment, Development, and Evaluation (GRADE) approach to assess the certainty of evidence and grade recommendations and the quality of reporting of each study based on the EQUATOR (Enhancing the QUAlity and Transparency Of health Research) network guidelines. The CPG addressed 21 questions and formulates 21 recommendations on the following domains: (1) definition; (2) phenotyping, and respiratory support strategies including (3) high-flow nasal cannula oxygen (HFNO); (4) non-invasive ventilation (NIV); (5) tidal volume setting; (6) positive end-expiratory pressure (PEEP) and recruitment maneuvers (RM); (7) prone positioning; (8) neuromuscular blockade, and (9) extracorporeal life support (ECLS). In addition, the CPG includes expert opinion on clinical practice and identifies the areas of future research.
Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.
The record
- Venue
- Intensive Care Medicine
- Topic
- Respiratory Support and Mechanisms
- Field
- Medicine
- Canadian institutions
- University of AlbertaSinai Health SystemToronto General HospitalUniversity of TorontoUniversity Health NetworkImpactSt. Michael's HospitalMcMaster University
- Funders
- National Heart, Lung, and Blood InstituteInstituto de Salud Carlos IIIMedical Research CouncilCanadian Institutes of Health ResearchGenentechGrifolsSwedish Orphan BiovitrumCenters for Disease Control and PreventionQueen's UniversityZonMwQueen's University BelfastNational Institute for Health and Care ResearchEisaiSOS OxygèneVir BiotechnologyNovavaxWorld Health OrganizationWellcome TrustNational Institutes of HealthRegeneron PharmaceuticalsEuropean Society of Intensive Care MedicineManitoba Health Research CouncilEuropean Respiratory SocietyNYU Langone Medical CenterEmory UniversityLeukemia and Lymphoma SocietyAlexion PharmaceuticalsEli Lilly and CompanyU.S. Department of DefenseAbiomedSanofiXeniosGlaxoSmithKlineLivaNovaAmerican Thoracic SocietyPfizerScience Foundation IrelandUK Research and InnovationNational Health and Medical Research CouncilAstraZenecaIntensive Care SocietyAmsterdam University Medical CentersGilead Sciences
- Keywords
- MedicinePain medicineAnesthesiologyAcute respiratory distressIntensive care medicineRespiratory distressRespiratory systemRespiratory diseaseMEDLINEEmergency medicineInternal medicineAnesthesiaLung
- Has abstract in OpenAlex
- yes