Gut Microbial Intersections with Human Ecology and Evolution
Bibliographic record
Abstract
Although microbiome science is relatively young, our knowledge of human-microbiome interactions is growing rapidly and has already begun to transform our understanding of human ecology and evolution. Here we summarize our current understanding of three-way interactions between the gut microbiota, human ecology, and human evolution. We review the factors driving microbiome variation within and between individuals and populations, as well as comparative data from nonhuman primates that allow a more direct examination of microbial relationships with host ecology and evolution. Collectively, these data sets can help illuminate generalizable principles governing host-microbiome-environment interactions, the processes contributing to bidirectional influences between the human gut microbiota and the human ecological niche, and past changes in the human microbiome that may have harbored consequences for human adaptation. Developing richer insight into host-microbiome-environment interactions will ultimately broaden our view of human biology and its response to changing environments.
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How this classification was reachedexpand
Full frame machine prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.
Distilled classifier scores by category (both heads)
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.001 | 0.002 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.001 | 0.000 |
| Bibliometrics | 0.001 | 0.002 |
| Science and technology studies | 0.001 | 0.004 |
| Scholarly communication | 0.004 | 0.003 |
| Open science | 0.000 | 0.002 |
| Research integrity | 0.002 | 0.003 |
| Insufficient payload (model declined to judge) | 0.003 | 0.001 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".