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Record W4391221568 · doi:10.7202/1108625ar

General Medical Practitioners Acting as Geneticists, a Risky Business?

2024· article· en· W4391221568 on OpenAlexaffvenueabout
Aurélie Dauge, Yann Joly, Beatrice Kaiser, Jocelyne Chiquette, Julie Lapointe, Jacques Simard, Michal Dorval, Hermann Nabi

Bibliographic record

VenueLex Electronica · 2024
Typearticle
Languageen
FieldBiochemistry, Genetics and Molecular Biology
TopicBRCA gene mutations in cancer
Canadian institutionsUniversité LavalCentre hospitalier de l'Université LavalUniversité de MontréalMcGill University Health Centre
Fundersnot available
KeywordsBusinessPsychology

Abstract

fetched live from OpenAlex

The availability of precision medicine tools and approaches has increased considerably over the past decades, propelled by rapid scientific advances in genomics and the popularity of direct-to-consumer genetic testing. Genetic specialists working within public healthcare systems are struggling to meet the growing demand for clinical genetic services. Some experts have suggested that doctors who are not specialized in genetics could take on some of the tasks performed by genetic specialists since they are regularly the first point of contact for people with a genetic predisposition to cancer. However, expanding doctors’ roles may heighten their standard of practice and concomitant medical liability risk to that of genetic specialists. This paper reviews the medical liability regime applicable to this situation through the lens of Canada’s unique bijural legal system. We then compare the state of the law in Canada to that of the United States. According to our findings, unless there is an improvement in the quality of genetic services provided by general practitioners, we could see a growing number of successful liability suits in clinical genetics and precision medicine in the coming years. To prevent this unsatisfactory outcome, additional professional training in core genetic tasks should be made increasingly available to general practitioners and the creation of communities of practice in genetics encouraged. Furthermore, courses introducing medical students to genetics, including its ethical and legal challenges, should be made available and actively promoted within medical curricula.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.008
metaresearch head score (Gemma)0.026
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Not applicable · Consensus signal: Not applicable
GenreCandidate signal: Commentary · Consensus signal: Commentary
Teacher disagreement score0.161
Threshold uncertainty score0.321

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0080.026
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0010.002
Science and technology studies0.0090.012
Scholarly communication0.0090.007
Open science0.0010.003
Research integrity0.0110.007
Insufficient payload (model declined to judge)0.0140.004

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.008
GPT teacher head0.302
Teacher spread0.294 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designNot applicable
Domainnot available
GenreCommentary

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations1
Published2024
Admission routes3
Has abstractyes

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Same venueLex ElectronicaSame topicBRCA gene mutations in cancerFrench-language works237,207