Gan-based data augmentation to improve breast ultrasound and mammography mass classification
Bibliographic record
Abstract
Data imbalance is a common problem in breast cancer diagnosis, to address this challenge, the research explores the use of Generative Adversarial Networks (GANs) to generate synthetic medical data. Various GAN methods, including Wasserstein GAN with Gradient Penalty (WGAN-GP), Cycle GAN, Conditional GAN, and Spectral Normalization GAN (SNGAN), were tested for data augmentation in breast regions of interest (ROIs) using mammography and ultrasound databases. The study employed real, synthetic, and hybrid ROIs (128x128 pixels) to train a Resnet network for classifying as benign (B) or malignant (M) classes. The quality and diversity of the synthetic data were assessed using several metrics: Fréchet Inception Distance (FID), Kernel Inception Distance (KID), Structural Similarity Index (SSIM), Multi-Scale SSIM (MS-SSIM), Blind Reference Image Spatial Quality Evaluator (BRISQUE), Naturalness Image Quality Evaluator (NIQE), and Perception-based Image Quality Evaluator (PIQE).Results revealed that the SNGAN model (FID = 52.89) was most effective for augmenting mammography data, while CGAN (FID = 116.03) excelled with ultrasound data. Cycle GAN and WGAN-GP, though demonstrating lower KID values, did not perform better than SNGAN and CGAN. The lower average MS-SSIM values suggested that SNGAN and CGAN produced a high diversity of synthetic images. However, lower SSIM, BRISQUE, NIQE, and PIQE values indicated poor quality in both real and synthetic images. Classification results showed high accuracy without data augmentation in both US (93.1 %B/94.9 %M) and mammography (80.9 %B/76.9 %M). The research concludes that preprocessing and characterizing ROIs by abnormality type is crucial to generate diverse synthetic data and improve accuracy in the classification process using combined GANs and CNN models.
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How this classification was reachedexpand
Full frame machine prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.
Distilled classifier scores by category (both heads)
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.001 | 0.003 |
| Meta-epidemiology (narrow) | 0.001 | 0.000 |
| Meta-epidemiology (broad) | 0.001 | 0.001 |
| Bibliometrics | 0.001 | 0.001 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.000 | 0.001 |
| Open science | 0.001 | 0.001 |
| Research integrity | 0.000 | 0.001 |
| Insufficient payload (model declined to judge) | 0.001 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".