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Record W4395107592 · doi:10.22175/mmb.17646

Title Pending 17646

2024· article· en· W4395107592 on OpenAlex

Why this work is in the frame

A frame that forgets how it found something cannot be audited. These are the routes that admitted this work.

affAt least one author lists a Canadian institution in the pinned OpenAlex snapshot.

Bibliographic record

VenueMeat and Muscle Biology · 2024
Typearticle
Languageen
FieldSocial Sciences
TopicIntellectual Property Law
Canadian institutionsUniversity of Guelph
Fundersnot available
KeywordsEnvironmental science

Abstract

fetched live from OpenAlex

This is an accepted article with a DOI pre-assigned that is not yet published.We aimed to assess the impact of vitamin A supplementation in beef cows at late gestation on intramuscular adipogenesis in the offspring. Thirty pregnant beef cows were randomly assigned to a control group (CONTROL, n = 15) fed a diet containing 4.1 KIU of vitamin A per kg, and to a vitamin A supplemented group (VITA, n = 15) fed a diet containing 12.2 KIU of vitamin A per kg. The treatment application occurred from 180 days of gestation until parturition. Calves were biopsied within 10 days of age to collect skeletal muscle samples for assessing gene expression and protein abundance of target genes/proteins related to adipogenesis. All calves were raised under the same conditions until slaughter. Cows from both treatments showed no differences (P > 0.05) in total gain and final body weight, although CONTROL cows exhibited greater (P = 0.03) dry matter intake. Skeletal muscle from calves VITA group exhibited increased mRNA expression of retinoic acid receptor β (RARβ; P = 0.02), while no differences (P > 0.05) were observed in mRNA expression of markers for adipo/fibrogenic cells (PDGFRα), and adipogenesis (ZFP423 and PPARγ). However, skeletal muscle from calves from VITA group showed greater protein abundance of DLK1 (P < 0.01) and PPARγ (P = 0.02) than those from CON group. No differences (P > 0.05) among treatments were observed in the abundance of RXR and PDGFRα. Repeated carcass ultrasound measurements of the offspring showed increased intramuscular fat content throughout all the evaluated stages of their post-natal life (P < 0.05), while no changes were observed within subcutaneous fat measurements (P > 0.05). Hot carcass weight, carcass yield and dressing percentage, and KPH fat percentage were not affected by treatment (P > 0.05). These findings suggest that vitamin A supplementation during late gestation enhances intramuscular adipogenesis in offspring.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesInsufficient payload (model declined to judge)
Consensus categoriesInsufficient payload (model declined to judge)
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Not applicable · Consensus signal: none
GenreCandidate signal: Other · Consensus signal: none
Teacher disagreement score0.964
Threshold uncertainty score1.000

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0050.001

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.046
GPT teacher head0.337
Teacher spread0.291 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it