O67 Differences in dietary intake patterns contribute to variations in the worldwide prevalence and severity of irritable bowel syndrome
Why this work is in the frame
A frame that forgets how it found something cannot be audited. These are the routes that admitted this work.
Bibliographic record
Abstract
<h3>Introduction</h3> Diet undoubtedly plays an important role in irritable bowel syndrome (IBS). Whether regional dietary habits influence the prevalence and severity of IBS remains unclear. We hypothesised that examining food frequency patterns may offer a more meaningful insight into this issue, and investigated whether distinct dietary clusters are associated with variation in the worldwide prevalence and severity of IBS. <h3>Methods</h3> 54,127 participants from 26 countries completed online questionnaires including the Rome IV diagnostic questionnaire and the consumption frequency of 10 food groups, as part of the Rome Foundation Global Epidemiology Study. Correspondence analysis, a data-driven clustering method based on latent class analysis (LCA) of the 10 food groups adjusted for Rome-IV IBS status and country, was employed to assess the separation of countries within these dietary clusters. <h3>Results</h3> We identified four unique clusters which demonstrated marked geographical and regional differences in dietary patterns worldwide and an association with relative IBS prevalence (figure 1). There was a significant difference in IBS prevalence between the four dietary pattern groups (P<0.001). Cluster A had the highest IBS prevalence at 5.5% (95%CI: 5.1–5.9) with a diet rich in bread, pasta, fruit and eggs, closely followed by Cluster B with a mean IBS prevalence of 5.0% (95%CI: 4.5 - 5.5) with diet including high consumption of dairy, fruits, and vegetables. Dietary clusters with the highest IBS prevalence (A and B) also had the highest mean IBS symptom severity scores (P<0.001), and were predominantly represented by South American, Latin American, African and Mediterranean countries (figure 1). These were followed by Cluster C predominantly represented by European and North American countries (USA and Canada), as well as Australia, with a mean IBS prevalence of 3.5% (95% CI: 3.3 - 3.7) and a diet characterised by lower consumption of tofu, rice, and eggs. Cluster D with the lowest IBS prevalence (2.6% (95%CI: 2.3 - 2.9) had a diet characterised by a high consumption of rice, eggs, fish, tofu, and vegetables, and was strongly represented by Asian countries. <h3>Conclusions</h3> This study demonstrates an association between dietary habits on the global prevalence and severity of IBS. These findings suggest that the approach to dietary management of IBS may need to be customised and adapted for different countries.
Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.
Full frame distilled prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.
Codex and Gemma teacher scores by category
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.000 | 0.000 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.000 | 0.000 |
| Bibliometrics | 0.000 | 0.000 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.000 | 0.000 |
| Insufficient payload (model declined to judge) | 0.000 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it