Protein Secondary Structure Prediction Using Convolutional Bidirectional GRU
Why this work is in the frame
A frame that forgets how it found something cannot be audited. These are the routes that admitted this work.
Bibliographic record
Abstract
In this paper, a protein secondary structure prediction method based on convolutional bidirectional GRU Model (CBi-GRU model) is adopted, which combines the advantages of sliding window in extracting local features of data. The use of CNN and Bi-GRU in the construction of the model improves the feature expression and data utilization, and improves the performance of the model. Protein data from FoxChase Institute were used, and high quality, complete and representative CullPDB dataset, CB513, CASP10 and CASP11 datasets were selected to train, test and validate the model. The results show that the proposed method achieves good prediction performance on CASP10 and CASP11 datasets, and the prediction accuracy of Q8 is 76.2% and 76.4%, respectively. Compared with RaptorX-SS, DeepCNF, CGAN-PSSP and other methods, the Q8 evaluation indicators are improved. Compared with the latest research data, our Q8 prediction accuracy is improved by 2% and 5.1%, which shows the effectiveness and superiority of the proposed model.
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Full frame distilled prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.
Codex and Gemma teacher scores by category
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.002 | 0.001 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.000 | 0.000 |
| Bibliometrics | 0.000 | 0.000 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.000 | 0.001 |
| Insufficient payload (model declined to judge) | 0.000 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it