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Microbrewidics: A Microfluidic Platform to Investigate What Stabilizes Hop Oil Emulsions in Beer

2024· article· en· W4403061778 on OpenAlex

Why this work is in the frame

A frame that forgets how it found something cannot be audited. These are the routes that admitted this work.

affAt least one author lists a Canadian institution in the pinned OpenAlex snapshot.
fundA Canadian funder is recorded on the work.

Bibliographic record

VenueACS Food Science & Technology · 2024
Typearticle
Languageen
FieldPharmacology, Toxicology and Pharmaceutics
TopicHops Chemistry and Applications
Canadian institutionsCanada Malting (Canada)University of Victoria
FundersCanadians for Leading Edge Alzheimer Research FoundationBritish Columbia Knowledge Development FundNatural Sciences and Engineering Research Council of CanadaCanada Research ChairsMichael Smith Health Research BCCanada Foundation for Innovation
KeywordsHop (telecommunications)MicrofluidicsNanotechnologyComputer scienceMaterials scienceTelecommunications

Abstract

fetched live from OpenAlex

Hop oils form microscopic emulsions in aqueous beer, but little is known about which molecules in beer stabilize these emulsions. Here we use a microfluidic platform as a tool to enable the creation of assays to explore the role of proteins in the stabilization of hop oil emulsions in beer. The terpenes linalool and α-pinene were used to form emulsions with a Kölsch-style ale on a microfluidic device (oil-in-beer emulsions). Gluten was added to these emulsions on-chip to investigate how this protein, which is present in beer, affects the stability of the emulsions. Then Brewers Clarex, an enzyme commonly used in brewing to degrade proteins, was added to digest the oil-in-beer emulsions. Our data suggest that the type and amount of proteins present in beer may affect the stability of the hop oil emulsions, which could have an impact on the shelf life and sensory quality of the beer.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesMeta-epidemiology (narrow)
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Bench or experimental · Consensus signal: Bench or experimental
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.269
Threshold uncertainty score1.000

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0010.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0010.006
Science and technology studies0.0000.002
Scholarly communication0.0000.001
Open science0.0010.001
Research integrity0.0010.001
Insufficient payload (model declined to judge)0.0000.001

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.087
GPT teacher head0.405
Teacher spread0.318 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it