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Record W4405750835 · doi:10.1016/j.procbio.2024.12.024

Valorization of fisheries by-products via enzymatic protein hydrolysis: A review of operating conditions, process design, and future trends

2024· review· en· W4405750835 on OpenAlex

Why this work is in the frame

A frame that forgets how it found something cannot be audited. These are the routes that admitted this work.

affAt least one author lists a Canadian institution in the pinned OpenAlex snapshot.
fundA Canadian funder is recorded on the work.

Bibliographic record

VenueProcess Biochemistry · 2024
Typereview
Languageen
FieldBiochemistry, Genetics and Molecular Biology
TopicProtein Hydrolysis and Bioactive Peptides
Canadian institutionsNational Research Council CanadaMemorial University of Newfoundland
FundersNational Research Council CanadaOcean Frontier InstituteNational Research Council
KeywordsProcess (computing)Biochemical engineeringEnzymatic hydrolysisChemistryHydrolysisBiotechnologyProcess engineeringComputer scienceEnvironmental scienceBiochemistryBiologyEngineering

Abstract

fetched live from OpenAlex

Fisheries by-products constitute large waste streams, despite containing protein, lipids, and other valuable compounds. The enzymatic protein hydrolysis process has been established as a means of effectively retrieving these products, though there has been little study to date on the impact of process operating conditions, pre-treatments, and process design on product quality. This review studies the impact of operating conditions relevant to the process, as well as the important parameters governing design and scale-up of the process. Findings indicate pre-treatments such as defatting, while common in literature, can limit the degree of hydrolysis of protein hydrolysates, while also conferring negative environmental impacts. Process conditions, such as temperature, pH, water ratios, and enzyme dose are typically established at lab scale, and can be at a disconnect with pilot and industrial scale studies. Furthermore, the water quality and pH control methods applied at lab scale are difficult to achieve at commercial scale. Current innovations involving endogenous fish enzymes and Enzyme Membrane Reactors may improve feasibility of this process in future, though these require more work. Enzyme hydrolysis is a promising technology for valorizing fisheries and other proteinaceous by-products and could see enhanced use in industry from further study on kinetics and scale-up.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesMeta-epidemiology (narrow)
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Bench or experimental · Consensus signal: none
GenreCandidate signal: Review · Consensus signal: Review
Teacher disagreement score0.692
Threshold uncertainty score1.000

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0010.000
Meta-epidemiology (broad)0.0010.000
Bibliometrics0.0000.001
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.014
GPT teacher head0.299
Teacher spread0.285 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it