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Record W4405750835 · doi:10.1016/j.procbio.2024.12.024

Valorization of fisheries by-products via enzymatic protein hydrolysis: A review of operating conditions, process design, and future trends

2024· review· en· W4405750835 on OpenAlexafffund
David T. Hopkins, Fabrice Berrué, Zied Khiari, Kelly Hawboldt

Bibliographic record

VenueProcess Biochemistry · 2024
Typereview
Languageen
FieldBiochemistry, Genetics and Molecular Biology
TopicProtein Hydrolysis and Bioactive Peptides
Canadian institutionsNational Research Council CanadaMemorial University of Newfoundland
FundersNational Research Council CanadaOcean Frontier InstituteNational Research Council
KeywordsProcess (computing)Biochemical engineeringEnzymatic hydrolysisChemistryHydrolysisBiotechnologyProcess engineeringComputer scienceEnvironmental scienceBiochemistryBiologyEngineering

Abstract

fetched live from OpenAlex

Fisheries by-products constitute large waste streams, despite containing protein, lipids, and other valuable compounds. The enzymatic protein hydrolysis process has been established as a means of effectively retrieving these products, though there has been little study to date on the impact of process operating conditions, pre-treatments, and process design on product quality. This review studies the impact of operating conditions relevant to the process, as well as the important parameters governing design and scale-up of the process. Findings indicate pre-treatments such as defatting, while common in literature, can limit the degree of hydrolysis of protein hydrolysates, while also conferring negative environmental impacts. Process conditions, such as temperature, pH, water ratios, and enzyme dose are typically established at lab scale, and can be at a disconnect with pilot and industrial scale studies. Furthermore, the water quality and pH control methods applied at lab scale are difficult to achieve at commercial scale. Current innovations involving endogenous fish enzymes and Enzyme Membrane Reactors may improve feasibility of this process in future, though these require more work. Enzyme hydrolysis is a promising technology for valorizing fisheries and other proteinaceous by-products and could see enhanced use in industry from further study on kinetics and scale-up.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.001
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Not applicable · Consensus signal: none
GenreCandidate signal: Review · Consensus signal: Review
Teacher disagreement score0.003
Threshold uncertainty score0.008

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0010.001
Meta-epidemiology (narrow)0.0010.001
Meta-epidemiology (broad)0.0020.001
Bibliometrics0.0030.004
Science and technology studies0.0000.001
Scholarly communication0.0010.002
Open science0.0010.001
Research integrity0.0010.002
Insufficient payload (model declined to judge)0.0020.002

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.014
GPT teacher head0.299
Teacher spread0.285 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designNot applicable
Domainnot available
GenreReview

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations9
Published2024
Admission routes2
Has abstractyes

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