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Population-based Study of Hypertrophic Pyloric Stenosis in Canada: Investigating the National Changes in Surgical Practice and Outcomes From 2004 to 2021

2025· article· en· W4406999488 on OpenAlex

Why this work is in the frame

A frame that forgets how it found something cannot be audited. These are the routes that admitted this work.

affAt least one author lists a Canadian institution in the pinned OpenAlex snapshot.
aboutThe title or abstract carries a Canadian signal from the geographic lexicon.

Bibliographic record

VenueJournal of Pediatric Surgery · 2025
Typearticle
Languageen
FieldMedicine
TopicIntestinal Malrotation and Obstruction Disorders
Canadian institutionsSickKids FoundationHospital for Sick ChildrenUniversity of Toronto
Fundersnot available
KeywordsMedicineHypertrophic Pyloric StenosisPyloric stenosisPopulationStenosisInternal medicineGeneral surgeryEnvironmental health

Abstract

fetched live from OpenAlex

BACKGROUND: Hypertrophic pyloric stenosis (HPS) is an acquired condition that causes gastric outlet obstruction in infants and requires operative treatment. We sought to explore the epidemiology, operative management and outcomes of HPS in Canada. METHODS: Canadian Institute for Health Information (CIHI) data for ICD-10 code for HPS and Canadian Classification of Health Interventions (CCI) code for pyloromyotomy in Canada (excluding Quebec) from 2004 to 2021 were obtained with REB approval. Data from 2004 to 2009, 2010-2015 and 2016-2021 were compared using Pearson's chi-square tests. Continuous variables were analyzed with one-way ANOVA tests. Significance was noted for p < 0.05. RESULTS: 6809 infants less than 12 months of age underwent pyloromyotomy for HPS from 2004 to 2021. The number of pyloromyotomies decreased when normalized to the national birth estimates over the study periods. 12.7 % of pyloromyotomies were performed laparoscopically from 2004 to 2009, and this increased to 47.4 % during 2016-2021. Pediatric surgeons performed 61 % of pyloromyotomies in 2004-2009 and this increased to 98 % of pyloromyotomies during the 2016 to 2021 period. There were no differences in the total length of stay (LOS) outcomes in the overall cohort, however, there was a statistically significant increase in the preoperative LOS outcomes in Ontario and the Prairies throughout the study periods. CONCLUSIONS: Despite a relatively stable number of births over a 17-year period in Canada, the number of pyloromyotomies has decreased. In Canada, pyloromyotomies are increasingly performed laparoscopically and almost exclusively by pediatric surgeons, which reflects the regionalization of pediatric surgical care. TYPE OF STUDY: Retrospective study. LEVEL OF EVIDENCE: Level III.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.007
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.046
Threshold uncertainty score0.890

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0010.007
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0010.001
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.031
GPT teacher head0.290
Teacher spread0.258 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it