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Record W4407409505 · doi:10.7554/elife.103339.1

Interpreting prediction intervals and distributions for decoding biological generality in meta-analyses

2025· preprint· en· W4407409505 on OpenAlexafffund
Yefeng Yang, Daniel W. A. Noble, Alistair M. Senior, Malgorzata Lagisz, Shinichi Nakagawa

Bibliographic record

VenueeLife · 2025
Typepreprint
Languageen
FieldComputer Science
TopicData Analysis with R
Canadian institutionsUniversity of Alberta
FundersCanada Excellence Research Chairs, Government of CanadaNational Natural Science Foundation of China
KeywordsGeneralityDecoding methodsStatisticsComputer scienceMathematicsEconometricsPsychology

Abstract

fetched live from OpenAlex

Abstract Despite the importance of identifying predictable regularities for knowledge transfer across contexts, the generality of ecological and evolutionary findings is yet to be systematically quantified. We present the first large-scale evaluation of generality using new metrics. By focusing on biologically relevant study levels, we show that generalization is not uncommon. Overall, 20% of meta-analyses will produce a non-zero effect 95% of the time in future replication studies with a 70% probability of observing meaningful effects in study-level contexts. We argue that the misconception that generalization is exceedingly rare is due to conflating within-study and between-study variances in ecological and evolutionary meta-analyses, which results from focusing too much on total heterogeneity (the sum of within-study and between-study variances). We encourage using our proposed approach to elucidate general patterns underpinning ecological and evolutionary phenomena.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.357
metaresearch head score (Gemma)0.755
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesMetaresearch
Consensus categoriesMetaresearch
DomainCandidate signal: Methods · Consensus signal: none
Study designCandidate signal: Theoretical or conceptual · Consensus signal: none
GenreCandidate signal: Methods · Consensus signal: Methods
Teacher disagreement score0.643
Threshold uncertainty score0.793

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.3570.755
Meta-epidemiology (narrow)0.0030.002
Meta-epidemiology (broad)0.0060.010
Bibliometrics0.0140.012
Science and technology studies0.0020.016
Scholarly communication0.0120.013
Open science0.0090.011
Research integrity0.0050.012
Insufficient payload (model declined to judge)0.0040.001

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.318
GPT teacher head0.440
Teacher spread0.122 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; the direct Gemma label and the distilled Codex classifier agree on what is shown here.

Study designTheoretical or conceptual
DomainMethods
GenreMethods

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations2
Published2025
Admission routes2
Has abstractyes

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