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Record W4408229973 · doi:10.1101/2025.02.28.640915

FASTiso: Fast Algorithm on Search state Tree for subgraph ISOmorphism in graphs of any size and density

2025· preprint· en· W4408229973 on OpenAlexaff
Wilfried Agbeto, Camille Coti, Vladimir Reinharz

Bibliographic record

VenuebioRxiv (Cold Spring Harbor Laboratory) · 2025
Typepreprint
Languageen
FieldComputer Science
TopicGraph Theory and Algorithms
Canadian institutionsÉcole de Technologie SupérieureUniversité du Québec à Montréal
Fundersnot available
KeywordsInduced subgraph isomorphism problemSubgraph isomorphism problemIsomorphism (crystallography)Tree (set theory)CombinatoricsMathematicsAlgorithmState (computer science)Computer scienceGraphLine graphChemistry

Abstract

fetched live from OpenAlex

Abstract Subgraph isomorphism is a fundamental combinatorial problem that involves finding one or more occurrences of a pattern graph within a target graph. It arises in a wide range of application domains, including biology, chemistry, social network analysis, and pattern recognition. Although subgraph isomorphism is NP-complete in the general case, many exact algorithms allow it to be solved in practice on many instances. However, the increasing size and structural diversity of graph datasets continue to pose significant challenges in terms of robustness and scalability. In this article, we propose FASTiso, an exact subgraph isomorphism algorithm that emphasizes a strong consistency between the variable ordering strategy and the pruning rules used during search. This design enables a unified exploitation of structural information throughout the exploration process, leading to improved efficiency and stable performance across heterogeneous graph structures. An extensive experimental evaluation on widely used synthetic and real-world benchmarks shows that FASTiso consistently outperforms reference solvers such as VF3, VF3L, and RI, and achieves competitive performance compared to constraint programming–based approaches (Glasgow, PathLad+), while outperforming them on most datasets. The results further demonstrate that FASTiso remains highly efficient on small instances and scales well to large graphs, while maintaining a lower memory footprint than most evaluated solvers. The peak memory usage is 7.74 GB for FASTiso, 36.19 GB for PathLad+, over 500 GB for Glasgow, 9.62 GB for VF3/VF3L, and 4.31 GB for RI. FASTiso code is available at https://gitlab.info.uqam.ca/cbe/fastiso as a C++ implementation, a Python module, and an integration within an extended version of NetworkX. The implementations support simple graphs and multigraphs, directed or undirected, with labels on nodes, edges, or both.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.004
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Simulation or modeling · Consensus signal: Simulation or modeling
GenreCandidate signal: Methods · Consensus signal: Methods
Teacher disagreement score0.016
Threshold uncertainty score0.055

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0010.004
Meta-epidemiology (narrow)0.0010.001
Meta-epidemiology (broad)0.0010.002
Bibliometrics0.0020.002
Science and technology studies0.0010.001
Scholarly communication0.0020.003
Open science0.0030.002
Research integrity0.0010.002
Insufficient payload (model declined to judge)0.0160.002

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.011
GPT teacher head0.221
Teacher spread0.210 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designSimulation or modeling
Domainnot available
GenreMethods

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2025
Admission routes1
Has abstractyes

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