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Record W4408367739 · doi:10.1007/s44163-025-00241-9

A review of machine learning and deep learning for Parkinson’s disease detection

2025· review· en· W4408367739 on OpenAlex

Why this work is in the frame

A frame that forgets how it found something cannot be audited. These are the routes that admitted this work.

affAt least one author lists a Canadian institution in the pinned OpenAlex snapshot.
fundA Canadian funder is recorded on the work.

Bibliographic record

VenueDiscover Artificial Intelligence · 2025
Typereview
Languageen
FieldMedicine
TopicParkinson's Disease Mechanisms and Treatments
Canadian institutionsUniversité de Moncton
FundersNatural Sciences and Engineering Research Council of Canada
KeywordsArtificial intelligenceComputer scienceParkinson's diseaseDiseaseDeep learningMachine learningNeurosciencePsychologyMedicinePathology

Abstract

fetched live from OpenAlex

Millions of people worldwide suffer from Parkinson's disease (PD), a neurodegenerative disorder marked by motor symptoms such as tremors, bradykinesia, and stiffness. Accurate early diagnosis is crucial for effective management and treatment. This article presents a novel review of Machine Learning (ML) and Deep Learning (DL) techniques for PD detection and progression monitoring, offering new perspectives by integrating diverse data sources. We examine the public datasets recently used in studies, including audio recordings, gait analysis, and medical imaging. We discuss the preprocessing methods applied, the state-of-the-art models utilized, and their performance. Our evaluation included different algorithms such as support vector machines (SVM), random forests (RF), convolutional neural networks (CNN). These algorithms have shown promising results in PD diagnosis with accuracy rates exceeding 99% in some studies combining data sources. Our analysis particularly showcases the effectiveness of audio analysis in early symptom detection and gait analysis, including the Unified Parkinson's Disease Rating Scale (UPDRS), in monitoring disease progression. Medical imaging, enhanced by DL techniques, has improved the identification of PD. The application of ML and DL in PD research offers significant potential for improving diagnostic accuracy. However, challenges like the need for large and diverse datasets, data privacy concerns, and data quality in healthcare remain. Additionally, developing explainable AI is crucial to ensure that clinicians can trust and understand ML and DL models. Our review highlights these key challenges that must be addressed to enhance the robustness and applicability of AI models in PD diagnosis, setting the groundwork for future research to overcome these obstacles.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.001
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesMeta-epidemiology (narrow)
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Not applicable · Consensus signal: none
GenreCandidate signal: Review · Consensus signal: Review
Teacher disagreement score0.860
Threshold uncertainty score1.000

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.001
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0020.001
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.050
GPT teacher head0.366
Teacher spread0.315 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it