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Record W4408615022 · doi:10.1287/msom.2023.0548

Policy Optimization for Personalized Interventions in Behavioral Health

2025· article· en· W4408615022 on OpenAlex

Why this work is in the frame

A frame that forgets how it found something cannot be audited. These are the routes that admitted this work.

affAt least one author lists a Canadian institution in the pinned OpenAlex snapshot.

Bibliographic record

VenueManufacturing & Service Operations Management · 2025
Typearticle
Languageen
FieldMathematics
TopicAdvanced Causal Inference Techniques
Canadian institutionsUniversity of Ottawa
Fundersnot available
KeywordsPsychological interventionPersonalized medicineBusinessComputer scienceOperations managementEconomicsMedicineNursing

Abstract

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Problem definition: Behavioral health interventions, delivered through digital platforms, have the potential to significantly improve health outcomes through education, motivation, reminders, and outreach. We study the problem of optimizing personalized interventions for patients to maximize a long-term outcome, in which interventions are costly and capacity constrained. We assume we have access to a historical data set collected from an initial pilot study. Methodology/results: We present a new approach for this problem that we dub [Formula: see text], which decomposes the state space for a system of patients to the individual level and then approximates one step of policy iteration. Implementing [Formula: see text] simply consists of a prediction task using the data set, alleviating the need for online experimentation. [Formula: see text] is a generic, model-free algorithm that can be used irrespective of the underlying patient behavior model. We derive theoretical guarantees on a simple, special case of the model that is representative of our problem setting. When the initial policy used to collect the data is randomized, we establish an approximation guarantee for [Formula: see text] with respect to the improvement beyond a null policy that does not allocate interventions. We show that this guarantee is robust to estimation errors. We then conduct a rigorous empirical case study using real-world data from a mobile health platform for improving treatment adherence for tuberculosis. Using a validated simulation model, we demonstrate that [Formula: see text] can provide the same efficacy as the status quo approach with approximately half the capacity of interventions. Managerial implications: [Formula: see text] is simple and easy to implement for an organization aiming to improve long-term behavior through targeted interventions, and this paper demonstrates its strong performance both theoretically and empirically, particularly in resource-limited settings. Funding: The authors are grateful for financial research support from the MIT Sloan Health Systems Initiative. Supplemental Material: The online appendix is available at https://doi.org/10.1287/msom.2023.0548 .

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Theoretical or conceptual · Consensus signal: Theoretical or conceptual
GenreCandidate signal: Methods · Consensus signal: Methods
Teacher disagreement score0.199
Threshold uncertainty score0.770

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0010.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.136
GPT teacher head0.465
Teacher spread0.329 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it