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Record W4408749824 · doi:10.1002/jeo2.70185

Effects of total knee arthroplasty on symptoms, function and activity over 5 years in knee osteoarthritis: A propensity‐score matched study

2025· article· en· W4408749824 on OpenAlex

Why this work is in the frame

A frame that forgets how it found something cannot be audited. These are the routes that admitted this work.

aboutThe title or abstract carries a Canadian signal from the geographic lexicon.
no affNo Canadian affiliation: this work is invisible to an affiliation-only frame.
No Canadian affiliation. An affiliation-only frame, the usual design, would never have seen this work. It is one of the works that make the case for inverting the frame.

Bibliographic record

VenueJournal of Experimental Orthopaedics · 2025
Typearticle
Languageen
FieldMedicine
TopicTotal Knee Arthroplasty Outcomes
Canadian institutionsnot available
Fundersnot available
KeywordsOsteoarthritisWOMACMedicinePropensity score matchingConfidence intervalPhysical therapyArthroplastyOrthopedic surgeryTotal knee arthroplastyMental healthKnee painInternal medicineSurgeryPsychiatry

Abstract

fetched live from OpenAlex

Abstract Purpose To evaluate the effects of total knee arthroplasty (TKA) on symptoms, function and activity over 5 years in knee osteoarthritis (KOA) patients. Methods Data were from the Osteoarthritis Initiative (OAI). Participants who conducted the first TKA from (not before) enrolment to 48 months were propensity score matching (PSM) on their characteristics at the visit before surgery (treated as baseline) to those who did not conduct a TKA at 48 months (treated as baseline). Changes in knee pain and functional disability were evaluated using the Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) pain and function subscales. Changes in physical activity, physical function and overall physical health and mental health were assessed using the Physical Activity Scale for the Elderly, the 20‐m walk speed and the five times chair‐to‐stand tests and the 12‐Item Short Form Survey, respectively. Results Eighty‐two pairs of participants in the TKA (56% women, mean 64.8 ± 8.4 years) and non‐TKA groups were matched. Knee symptoms were significantly improved in the TKA group and flatted from 24 months (Pain: β = −3.29, 95% confidence interval [CI] = [−4.59 to −1.99], p < 0.001; Function: β = −10.12, 95% CI = [−14.21 to −6.03], p < 0.001). Physical function and overall physical health but not physical activity or mental health (PASE: β = 5.72, 95% CI = [−15.46 to 26.90], p = 0.597; Mental: β = 0.04, 95% CI = [−2.47 to 2.54], p = 0.976) was improved in the TKA group over 24 months. Conclusions TKA substantially improved knee symptoms and physical function over 60 months and physical health over 48 months, compared to those who had a similar severity of KOA but did not have a TKA, but this did not translate into increased physical activity or mental health. Level of Evidence Level III.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.047
Threshold uncertainty score0.890

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0010.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.001
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.010
GPT teacher head0.261
Teacher spread0.251 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it