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Record W4409228807 · doi:10.2106/jbjs.oa.24.00065

Rethinking the Paradigm of Using Ps for Diagnosing Compartment Syndrome

2025· article· en· W4409228807 on OpenAlex

Why this work is in the frame

A frame that forgets how it found something cannot be audited. These are the routes that admitted this work.

affAt least one author lists a Canadian institution in the pinned OpenAlex snapshot.
aboutThe title or abstract carries a Canadian signal from the geographic lexicon.

Bibliographic record

VenueJBJS Open Access · 2025
Typearticle
Languageen
FieldMedicine
TopicMuscle and Compartmental Disorders
Canadian institutionsMcGill University Health Centre
FundersOffice of the Under Secretary of Defense
KeywordsPallorMedicinePalpationGold standard (test)FasciotomyParalysisRetrospective cohort studyPhysical therapySurgeryInternal medicineClinical trial

Abstract

fetched live from OpenAlex

Background: To evaluate the predictive power of 7 clinical signs and symptoms associated with acute compartment syndrome (ACS) of the leg, namely pain, paresthesia, paralysis, pallor, poikilothermia, pulselessness, and pressure on palpation (7P's). Methods: Retrospective data of 357 patients were obtained from the databases of 5-level one trauma centers in Canada, the United States, and France. Inclusion criteria were patients with tibia injuries that received fasciotomies in adults with documented serial clinical assessments. All possible combinations of signs/symptoms used were generated. The combinations were tested for predictive power using 2 machine learning algorithms. Results: Pressure on palpation was the strongest clinical predictor of ACS while pain was the weakest. Using any single P to assess for ACS yields a poor prediction. Increasing the number of Ps improves the performance up to 4Ps, regardless of the composition of the combination. None of the combinations had a perfect predictive power which means that the use of single or multiple Ps does not guarantee diagnosis. Predictive performance indicated that poikilothermia, pallor, and paralysis are not significantly informative. Conclusion: The presence of specific patterns of clinical signs/symptoms associated with ACS seems to influence a surgeon's decision to perform fasciotomy. These data question the gold standard of clinical signs for diagnosis of ACS. The reliance on the Ps classically taught in medical school does not seem to be sufficient for accurate diagnosis. Objective measures such as continuous pressure or a physiologic marker of ischemia may be better indications for compartment syndrome. Level of Evidence: Level III. See Instructions for Authors for a complete description of levels of evidence.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.053
Threshold uncertainty score0.333

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0010.001
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.187
GPT teacher head0.483
Teacher spread0.296 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it