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Advancing interpretable cardiac disease diagnosis via a transformer-convolutional hybrid network on electrocardiograms

2025· article· en· W4409346796 on OpenAlex

Why this work is in the frame

A frame that forgets how it found something cannot be audited. These are the routes that admitted this work.

affAt least one author lists a Canadian institution in the pinned OpenAlex snapshot.

Bibliographic record

VenueEngineering Applications of Artificial Intelligence · 2025
Typearticle
Languageen
FieldMedicine
TopicECG Monitoring and Analysis
Canadian institutionsMcGill UniversityMontreal Neurological Institute and Hospital
FundersChina Scholarship CouncilNational Natural Science Foundation of China
KeywordsComputer scienceTransformerArtificial intelligenceConvolutional neural networkPattern recognition (psychology)Electrical engineeringVoltage

Abstract

fetched live from OpenAlex

Manual heart disease diagnosis with the electrocardiogram (ECG) is intractable due to the intertwined signal features and lengthy diagnosis procedure, especially for the 24-hour dynamic ECG signals. Consequently, even experienced cardiologists may face difficulty in producing all accurate ECG reports. In recent years, Artificial Intelligence (AI), particularly neural network-based automatic ECG diagnosis methods have exhibited promising performance, suggesting a potential alternative to the labor-intensive examination conducted by cardiologists. However, many existing approaches failed to adequately consider the temporal and channel dimensions when assembling features and ignored interpretability. And clinical theory underscores the necessity of prolonged signal observations for diagnosing certain ECG conditions such as tachycardia. Moreover, specific heart diseases manifest primarily through distinct ECG leads represented as channels. In response to these challenges, this paper introduces a novel neural network architecture for ECG classification (diagnosis). The proposed model incorporates Lead Fusing blocks, transformer-XL (meaning extra long) encoder-based Encoder modules, and hierarchical temporal attentions. Importantly, this classifier operates directly on raw ECG time-series signals rather than cardiac cycles. Signal integration begins with the Lead Fusing blocks, followed by the Encoder modules and hierarchical temporal attentions, enabling the extraction of long-dependent features. Furthermore, existing convolution-based methods have been argued to compromise interpretability, whereas the proposed neural network provides improved clarity in this regard. Experimental evaluations on a comprehensive public dataset confirm the superiority of the proposed classifier over state-of-the-art methods. Moreover, a visualization method was employed to generate a location map that demonstrates the areas of the signal emphasized by the model, thereby enhancing interpretability. • Our model extracts long-dependent features of ECG signals based on the Transformer-XL encoder. • The proposed network offers the improved interpretability. • Our classifier achieves superior performance over other state-of-the-art methods.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Simulation or modeling · Consensus signal: Simulation or modeling
GenreCandidate signal: Empirical · Consensus signal: none
Teacher disagreement score0.974
Threshold uncertainty score0.690

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.001
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.006
GPT teacher head0.260
Teacher spread0.255 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it