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Record W4410236631 · doi:10.1016/j.imu.2025.101651

The role of machine learning in infectious disease early detection and prediction in the MENA region: A systematic review

2025· review· en· W4410236631 on OpenAlex

Why this work is in the frame

A frame that forgets how it found something cannot be audited. These are the routes that admitted this work.

affAt least one author lists a Canadian institution in the pinned OpenAlex snapshot.
fundA Canadian funder is recorded on the work.

Bibliographic record

VenueInformatics in Medicine Unlocked · 2025
Typereview
Languageen
FieldMedicine
TopicCOVID-19 diagnosis using AI
Canadian institutionsYork University
FundersInternational Development Research Centre
KeywordsInfectious disease (medical specialty)Artificial intelligenceDiseaseMachine learningComputer scienceMedicinePathology

Abstract

fetched live from OpenAlex

This systematic review analyzes the implementation and effectiveness of machine learning (ML) approaches for infectious disease surveillance and prediction across the Middle East and North Africa (MENA) region. Adhering to PRISMA guidelines, studies published between 2016 and 2024 were examined to assess model structures, performance metrics, and dataset characteristics. The findings reveal a predominance of deep learning approaches, particularly Convolutional Neural Networks (CNNs), achieving mean accuracy rates of 96.3 % in pathogen detection from medical imaging. Random Forest algorithms demonstrated superior performance in disease outbreak prediction, with mean ACC scores of 0.85. Iran, Saudi Arabia, and Egypt emerged as regional leaders, collectively contributing 54 % of the analyzed studies. The temporal analysis showed peak research output in 2022 (n = 30 studies), followed by a 25 % decline in 2023. Despite promising performance, challenges such as data quality, infrastructural limitations, and algorithmic bias persist. This review highlights the need for standardized protocols, enhanced digital infrastructure, and collaborative efforts to realize the full potential of ML in enhancing public health interventions across the region. Future research directions should prioritize multi-center validation studies, standardized reporting frameworks, and integration of diverse data modalities to enhance model robustness and clinical applicability.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.004
metaresearch head score (Gemma)0.012
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesMetaresearch
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Systematic review · Consensus signal: Systematic review
GenreCandidate signal: Review · Consensus signal: Review
Teacher disagreement score0.107
Threshold uncertainty score0.997

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0040.012
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0030.000
Bibliometrics0.0010.002
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.001
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.019
GPT teacher head0.322
Teacher spread0.303 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it