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Record W4410910001 · doi:10.7759/cureus.85155

Complications Following Local-Flap Lip Reconstruction After Tumor Removal: A Systematic Review

2025· review· en· W4410910001 on OpenAlex

Why this work is in the frame

A frame that forgets how it found something cannot be audited. These are the routes that admitted this work.

affAt least one author lists a Canadian institution in the pinned OpenAlex snapshot.

Bibliographic record

VenueCureus · 2025
Typereview
Languageen
FieldMedicine
TopicReconstructive Facial Surgery Techniques
Canadian institutionsUniversity of Toronto
Fundersnot available
KeywordsMedicineSurgeryGeneral surgery

Abstract

fetched live from OpenAlex

Local flap reconstruction plays a critical role in managing defects following lip tumor removal. The aim of this review is to evaluate complications associated with local flap reconstruction for lip tumor removal. A systematic review was conducted utilizing the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines. The PubMed (MEDLINE) database was queried from 2014 to 2024 with the following keywords: ("lip reconstruction" OR "cheiloplasty" OR "local flap") AND ("outcomes" OR "functional" OR "postoperative" OR "complications" OR "clinical"). Only retrospective and prospective studies, case series, randomized controlled trials, original research, and studies with patients requiring local flap reconstruction for tumor removal were included. We excluded studies that were related to cleft lip reconstruction, lip infection, burns, arteriovenous malformations (AVM), animal studies, technical reports, cadaveric studies, case reports, and review articles. After removal of duplicates and screening of titles, abstracts, and full-length text, 18 of the 749 initial articles were included in this review. The mean age across the articles was 66 ± 8 years (253 males; 124 females) with an average follow-up time of 23 ± 10 months. All of the studies included patients with squamous cell carcinoma (SCC), and only six of them analyzed patients with basal cell carcinoma (BCC). All studies included patients with bottom lip pathology, and only three with top lip pathology. The mean complication rate was 8% across the studies. The most common reported complication was wound dehiscence (9/18), followed by paresthesias (7/18), microstomia (5/18), sialorrhea (4/18), and flap necrosis (2/18). The most common local flaps included: seven instances of Karapandzic, four instances of Abbe flaps, one case of Yu flap, two instances of step technique flaps, one case of Gillies flap, and two mentions of Webster flaps. Complications were reported in nine of the 19 articles. Local flap techniques provide favorable aesthetic and functional outcomes in lip reconstruction. However, current outcome measures vary widely, often including aesthetic evaluations, functional assessments, and complication rates, without standardized reporting. To enhance comparability and improve practice, surgeons should adopt standardized frameworks for reporting outcomes, such as validated tools for aesthetic and functional assessment (e.g., FACE-Q, PROMIS). Incorporating pre- and postoperative patient-reported outcomes, uniform complication classifications, and multi-center data collaboration will enable more consistent evidence-based decision-making and optimize patient care. Future studies should seek to utilize these practices for uniform reporting and improving patient outcomes.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.001
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesMeta-epidemiology (narrow)
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Systematic review · Consensus signal: Systematic review
GenreCandidate signal: Review · Consensus signal: Review
Teacher disagreement score0.319
Threshold uncertainty score1.000

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0010.001
Meta-epidemiology (narrow)0.0010.001
Meta-epidemiology (broad)0.0060.002
Bibliometrics0.0000.001
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.001
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.031
GPT teacher head0.354
Teacher spread0.323 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it