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Record W4411000348 · doi:10.2341/24-090-c

Effects of Catalyst Bioproducts on In-Office Whitening: A Randomized, Split-mouth Clinical Analysis

2025· article· en· W4411000348 on OpenAlex

Why this work is in the frame

A frame that forgets how it found something cannot be audited. These are the routes that admitted this work.

affAt least one author lists a Canadian institution in the pinned OpenAlex snapshot.

Bibliographic record

VenueOperative Dentistry · 2025
Typearticle
Languageen
FieldDentistry
TopicDental Erosion and Treatment
Canadian institutionsUniversity of Toronto
Fundersnot available
KeywordsBioproductsRandomized controlled trialDentistryMedicineWaste managementInternal medicineEngineering

Abstract

fetched live from OpenAlex

OBJECTIVES: To compare conventional hydrogen peroxide (H2O2) whitening therapy (CT) applied for 45 minutes with a test therapy (TT) containing H2O2 whitening gel and catalyst bioproducts applied for 15 minutes. METHODS: Thirty patients and their hemiarches were randomly divided into two groups: CT: application of 35% H2O2 three times for 15 minutes; test therapy (TT): based on the prior application of a polycaprolactone scaffold and the addition of 10 mg of peroxidase to the 35% whitening gel (3 drops of thickener, 9 drops of peroxide and 10 mg of peroxidase) for an exposure time of 15 minutes.The two treatments were carried out in three whitening sessions, 7 days apart. The chromatic change (ΔE00) and the bleaching index (ΔWID) were analyzed by spectrophotometry. Spontaneous sensitivity was assessed through a questionnaire, and thermal sensitivity was provoked through thermal stimuli after the three sessions and 14 days later. Esthetic self-perception was also measured using the Orofacial Esthetics Scale before and after each session. RESULTS: After the first session, CT exceeded TT in ΔE00 and ΔWID, whereas they were equal at the other time points. Greater intensity and occurrence of spontaneous sensitivity occurred in the first and second sessions with CT. The CT group experienced thermal sensitivity at higher temperatures than the TT group at all times analyzed. Esthetic self-perception was higher (66.6%) in the TT group. CONCLUSION: The test therapy can achieve the same whitening effect with less total exposure time and less tooth sensitivity than the conventional technique.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.001
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesMeta-epidemiology (narrow)
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.178
Threshold uncertainty score1.000

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0010.001
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0010.001
Bibliometrics0.0000.002
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.015
GPT teacher head0.362
Teacher spread0.347 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it