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Prevalence and factors associated with early neonatal sepsis in a neonatal intensive care unit in Medellín, Colombia

2024· article· en· W4411689818 on OpenAlex

Why this work is in the frame

A frame that forgets how it found something cannot be audited. These are the routes that admitted this work.

venuePublished in a venue whose home country is Canada.
no affNo Canadian affiliation: this work is invisible to an affiliation-only frame.
No Canadian affiliation. An affiliation-only frame, the usual design, would never have seen this work. It is one of the works that make the case for inverting the frame.

Bibliographic record

VenueCanadian Journal of Infection Control · 2024
Typearticle
Languageen
FieldMedicine
TopicNeonatal and Maternal Infections
Canadian institutionsnot available
Fundersnot available
KeywordsNeonatal intensive care unitNeonatal sepsisMedicineSepsisIntensive care unitPediatricsIntensive care medicineInternal medicine

Abstract

fetched live from OpenAlex

Background: Early neonatal sepsis poses a significant public health challenge worldwide, especially in Colombia and Latin America. It remains a leading cause of morbidity and mortality among newborns, particularly affecting those born prematurely or with low birth weights. Despite advancements in care and preventive strategies, the prevalence of sepsis continues to be alarming. Methods: A descriptive study employing retrospective data was conducted in the PROCAREN Neonatal Intensive Care Unit (NICU) from May 2015 to January 2018. The study aimed to assess the prevalence and identify factors associated with early neonatal sepsis. A total of 88 medical records of neonates diagnosed with sepsis, either clinically or microbiologically, were reviewed, excluding those with incomplete records. Results: Of the neonates studied, 55% were male, and 56% resided outside the metropolitan area. Maternal risk factors identified included chorioamnionitis (85.7%) and nearly half (46%) of women did not receive full prenatal care. Neonatal risk factors included pre-term birth (52.3%), low birth weight (49%), and a 5.7% mortality rate due to sepsis. Additionally, 37 neonates exhibited factors associated with early sepsis, with higher prevalence rates of hypoglycemia (29.7%), pneumonia (24.3%), and urinary tract infections (13.5%). Conclusions: Our findings corroborate those in the literature, emphasizing socio-demographic and neonatal risk factors for early neonatal sepsis. Notable maternal factors identified included chorioamnionitis and prolonged rupture of membranes, while the main neonatal factors were pre-term birth and low birth weight. Despite preventive measures, high incidence and mortality rates due to sepsis persist, underscoring the importance of addressing these factors to improve neonatal outcomes.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.236
Threshold uncertainty score0.977

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0010.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.001
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.015
GPT teacher head0.246
Teacher spread0.232 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it