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Record W4412857031 · doi:10.1186/s43058-025-00765-2

Leveraging intermediaries’ skillsets to build implementation research and practice infrastructure: a qualitative case study

2025· article· en· W4412857031 on OpenAlex

Why this work is in the frame

A frame that forgets how it found something cannot be audited. These are the routes that admitted this work.

affAt least one author lists a Canadian institution in the pinned OpenAlex snapshot.
fundA Canadian funder is recorded on the work.
aboutThe title or abstract carries a Canadian signal from the geographic lexicon.

Bibliographic record

VenueImplementation Science Communications · 2025
Typearticle
Languageen
FieldHealth Professions
TopicHealth Policy Implementation Science
Canadian institutionsUniversity of CalgaryAlberta HealthUniversity of Alberta
FundersCanadian Institutes of Health ResearchAlberta Children's Hospital Research InstituteAlberta InnovatesChildren's Hospital FoundationPublic Health AgencyUniversity of AlbertaAthabasca UniversityPublic Health Agency of CanadaStollery Children’s Hospital FoundationWomen and Children's Health Research InstituteUniversity of LethbridgeChildren's Health Research InstituteKillam TrustsAlberta Health Services
KeywordsIntermediaryQualitative researchBusinessCritical infrastructureKnowledge managementProcess managementPublic relationsComputer scienceSociologyComputer securityPolitical scienceMarketingSocial science

Abstract

fetched live from OpenAlex

BACKGROUND: Implementation science as a field is rapidly advancing. Moreover, implementation science plays a pivotal role in driving learning health systems to better realize health outcomes and impact for our communities. Yet, few reports detail the infrastructures that underpin embedding and managing implementation science activities. Furthermore, there is little guidance for designing these infrastructures (people-powered and/or inanimate supports essential for embedding implementation research questions in pilot, spread and scale initiatives) to address local research and practice needs. The Implementation Science Collaborative is one such infrastructure in Alberta, Canada that leverages existing expertise in implementation research and practice to facilitate embedded implementation research and increase the success rates of health innovation implementation for better health outcomes. This study sought to provide actionable recommendations for designing effective implementation infrastructure by examining the co-design of the Implementation Science Collaborative. METHODS: We conducted a longitudinal case study (2018-2021) of the Implementation Science Collaborative using document analysis and semi-structured interviews. We collected data from initiative planning and operations documents (n = 190) and semi-structured interviews with Implementation Science Collaborative members (n = 6). We applied the Large-Scale Change Driver Model as the analytical framework for qualitative analysis to generate insights into designing cross-sectoral implementation science infrastructure. RESULTS: Our analysis showed that infrastructure design and operationalization followed established principles of implementation planning and execution. Implementation intermediaries proved to be effective facilitators as they had the backgrounds required to guide co-design and implementation planning. Their political neutrality in the resulting infrastructure enabled them to address power imbalances among co-design partners. However, strong management leadership remained irreplaceable. Cross-sectoral leadership was essential in fostering and solidifying the partnerships required for supporting the local learning health system. CONCLUSION: The study findings highlight the effectiveness of a co-design approach, facilitated by intermediaries, in developing local implementation science infrastructure and management systems as a promising practice to implement for achieving outcomes. This approach enabled the creation of infrastructure designs that meet diverse user needs. However, co-design is a complex process that benefits from both intermediaries' skills and cross-sectoral leadership knowledge of the local learning health system.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.033
metaresearch head score (Gemma)0.011
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesMetaresearch, Science and technology studies
Consensus categoriesMetaresearch
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Qualitative · Consensus signal: Qualitative
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.075
Threshold uncertainty score0.998

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0330.011
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0020.007
Science and technology studies0.0100.002
Scholarly communication0.0000.002
Open science0.0020.003
Research integrity0.0000.001
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.750
GPT teacher head0.824
Teacher spread0.073 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it