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Record W4412857031 · doi:10.1186/s43058-025-00765-2

Leveraging intermediaries’ skillsets to build implementation research and practice infrastructure: a qualitative case study

2025· article· en· W4412857031 on OpenAlexafffundabout
Stephanie Brooks, Cody Alba, Stephanie Montesanti, Denise Thomson, Sara N. Davison, Kathryn Graham, Kate Storey

Bibliographic record

VenueImplementation Science Communications · 2025
Typearticle
Languageen
FieldHealth Professions
TopicHealth Policy Implementation Science
Canadian institutionsUniversity of CalgaryAlberta HealthUniversity of Alberta
FundersCanadian Institutes of Health ResearchAlberta Children's Hospital Research InstituteAlberta InnovatesChildren's Hospital FoundationPublic Health AgencyUniversity of AlbertaAthabasca UniversityPublic Health Agency of CanadaStollery Children’s Hospital FoundationWomen and Children's Health Research InstituteUniversity of LethbridgeChildren's Health Research InstituteKillam TrustsAlberta Health Services
KeywordsIntermediaryQualitative researchBusinessCritical infrastructureKnowledge managementProcess managementPublic relationsComputer scienceSociologyComputer securityPolitical scienceMarketingSocial science

Abstract

fetched live from OpenAlex

BACKGROUND: Implementation science as a field is rapidly advancing. Moreover, implementation science plays a pivotal role in driving learning health systems to better realize health outcomes and impact for our communities. Yet, few reports detail the infrastructures that underpin embedding and managing implementation science activities. Furthermore, there is little guidance for designing these infrastructures (people-powered and/or inanimate supports essential for embedding implementation research questions in pilot, spread and scale initiatives) to address local research and practice needs. The Implementation Science Collaborative is one such infrastructure in Alberta, Canada that leverages existing expertise in implementation research and practice to facilitate embedded implementation research and increase the success rates of health innovation implementation for better health outcomes. This study sought to provide actionable recommendations for designing effective implementation infrastructure by examining the co-design of the Implementation Science Collaborative. METHODS: We conducted a longitudinal case study (2018-2021) of the Implementation Science Collaborative using document analysis and semi-structured interviews. We collected data from initiative planning and operations documents (n = 190) and semi-structured interviews with Implementation Science Collaborative members (n = 6). We applied the Large-Scale Change Driver Model as the analytical framework for qualitative analysis to generate insights into designing cross-sectoral implementation science infrastructure. RESULTS: Our analysis showed that infrastructure design and operationalization followed established principles of implementation planning and execution. Implementation intermediaries proved to be effective facilitators as they had the backgrounds required to guide co-design and implementation planning. Their political neutrality in the resulting infrastructure enabled them to address power imbalances among co-design partners. However, strong management leadership remained irreplaceable. Cross-sectoral leadership was essential in fostering and solidifying the partnerships required for supporting the local learning health system. CONCLUSION: The study findings highlight the effectiveness of a co-design approach, facilitated by intermediaries, in developing local implementation science infrastructure and management systems as a promising practice to implement for achieving outcomes. This approach enabled the creation of infrastructure designs that meet diverse user needs. However, co-design is a complex process that benefits from both intermediaries' skills and cross-sectoral leadership knowledge of the local learning health system.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.059
metaresearch head score (Gemma)0.057
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Qualitative · Consensus signal: Qualitative
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.059
Threshold uncertainty score0.313

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0590.057
Meta-epidemiology (narrow)0.0010.001
Meta-epidemiology (broad)0.0010.001
Bibliometrics0.0030.003
Science and technology studies0.0180.015
Scholarly communication0.0080.007
Open science0.0040.013
Research integrity0.0040.006
Insufficient payload (model declined to judge)0.0060.001

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.750
GPT teacher head0.824
Teacher spread0.073 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designQualitative
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

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Citations2
Published2025
Admission routes3
Has abstractyes

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