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Record W4413480847 · doi:10.1101/2025.08.20.25334071

The impact of virtual reality cognitive behavioral therapy on mental disorders among children and youth: a systematic review and meta-analysis

2025· preprint· en· W4413480847 on OpenAlex

Why this work is in the frame

A frame that forgets how it found something cannot be audited. These are the routes that admitted this work.

affAt least one author lists a Canadian institution in the pinned OpenAlex snapshot.

Bibliographic record

VenuemedRxiv · 2025
Typepreprint
Languageen
FieldBusiness, Management and Accounting
TopicVaried Academic Research Topics
Canadian institutionsWestern University
Fundersnot available
KeywordsMeta-analysisCognitionPsychologyVirtual realityClinical psychologyMedicinePsychiatryComputer scienceHuman–computer interaction

Abstract

fetched live from OpenAlex

Abstract Background Cognitive behavioral therapy (CBT) is an effective treatment for mental disorders, however, it can be associated with limited patient engagement, low adherence, and stigma among younger populations. Virtual reality (VR) environments can facilitate innovative approaches to enhance CBT implementation in a controlled and immersive way. Objectives This study evaluates the impact of VR-CBT interventions on mental disorders in children and youth through a systematic review and meta-analysis. Methods A search was conducted in PsycINFO, PubMed, EMBASE, Scopus, and Web of Science. Studies compared VR-CBT interventions to traditional therapy or control conditions. Extracted data included post-intervention means, standard deviations, and 95% confidence intervals. Pooled effect sizes were calculated using Hedges’ g and analyzed with a random-effects model. Risk of bias was evaluated using the Cochrane risk-of-bias (RoB) 2 tool and the JBI Critical Appraisal Tool. Results In total, 20 studies were included in the systematic review, with 85% (n = 17) utilizing virtual reality exposure therapy (VRET), and 15% (n = 3) implementing broader VR-CBT frameworks. VR technologies included wearable head-mounted displays (70%, n = 14), with 30% (n = 6) relying on non-wearable systems, and 15% (n = 3) incorporating gamification elements. Seven studies were included in a meta-analysis, which showed that VR-CBT was associated with a small to moderate reduction in mental disorder symptoms in full-scale studies (pooled Hedge’s g = -0.46 (95% CI: [-0.84], [-0.09]). Conclusions VR-CBT interventions demonstrate potential for addressing mental disorders in children and youth, particularly when traditional therapy alone is insufficient and/or inaccessible.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.002
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.166
Threshold uncertainty score1.000

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0020.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0020.001
Bibliometrics0.0000.001
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.001
Research integrity0.0000.001
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.084
GPT teacher head0.369
Teacher spread0.285 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it