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Record W4414541745 · doi:10.1038/s41538-025-00549-x

Potential health benefits of insect bioactive metabolites and consumer attitudes towards edible insects

2025· review· en· W4414541745 on OpenAlex

Why this work is in the frame

A frame that forgets how it found something cannot be audited. These are the routes that admitted this work.

affAt least one author lists a Canadian institution in the pinned OpenAlex snapshot.

Bibliographic record

Venuenpj Science of Food · 2025
Typereview
Languageen
FieldAgricultural and Biological Sciences
TopicInsect Utilization and Effects
Canadian institutionsMinistère de l'Agriculture, des Pêcheries et de l'AlimentationMcGill University
FundersJomo Kenyatta University of Agriculture and Technology
KeywordsHealth benefitsInsectDesmosterolBioactive compoundProbioticGlycemic

Abstract

fetched live from OpenAlex

Particular attention has been paid to the nutritional potential of edible insects as well as the health benefits associated with their bioactive compounds. This paper focused on an in-depth review compiling the most recent information on health benefits of insect bioactive metabolites as well as their purification and identification, in addition to consumer attitudes towards edible insects. It was found that, insect bioactive metabolites, including marcocarpal, grandinol, trolline, pancratistatin, narciclasin, ungeremin, cantharidin, cordycepin, roseoflavin, lecithin, reblastatin, chitin, chitosan and desmosterol deemed to have biological activities, such as tumor suppression, anticancer, antihypertensive, anti-inflammatory, antioxidant, immunomodulator, neuroprotective, glycemic and lipid regulation, blood pressure reduction, regulation of intestinal bacterial flora and cardiovascular protection among others. Furthermore, proper sample preparation and extraction is the first step in the purification of bioactive metabolites from edible insects. After concentration, bioactive metabolites are purified using chromatographic and separation techniques including High-Performance Liquid Chromatography (HPLC), Gas Chromatography (GC), Thin-Layer Chromatography (TLC), Size-Exclusion Chromatography (SEC). Finally, their nutritional potential, health benefits, environmentally friendly, great taste, traditions, taboo, safety concerns, unpleasant past experiences, allergies, and unnaturalness are among the main factors influencing attitudes towards insect consumption.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Other design · Consensus signal: none
GenreCandidate signal: Review · Consensus signal: Review
Teacher disagreement score0.986
Threshold uncertainty score0.424

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0010.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0010.000
Bibliometrics0.0000.002
Science and technology studies0.0000.001
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.057
GPT teacher head0.314
Teacher spread0.257 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it