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Record W4415039941 · doi:10.1136/bmjhci-2024-101418

Machine learning model to classify chronic leg wounds and identify pyoderma gangrenosum

2025· article· en· W4415039941 on OpenAlex

Why this work is in the frame

A frame that forgets how it found something cannot be audited. These are the routes that admitted this work.

affAt least one author lists a Canadian institution in the pinned OpenAlex snapshot.

Bibliographic record

VenueBMJ Health & Care Informatics · 2025
Typearticle
Languageen
FieldMedicine
TopicWound Healing and Treatments
Canadian institutionsMila - Quebec Artificial Intelligence Institute
FundersBundesministerium für Bildung und Forschung
KeywordsPyoderma gangrenosumLeg ulcerFoot (prosody)Wound careClinical PracticeChronic wound

Abstract

fetched live from OpenAlex

STUDY OBJECTIVES: Chronic wounds represent a significant economic and personal burden. For their successful treatment, the causes must be known and treated. Wounds caused by pyoderma gangrenosum (PG), a rare inflammatory skin disease, are often misdiagnosed. This study, therefore, aims to develop a machine learning model capable of differentiating PG from other wound types, focusing on chronic leg wounds to address this diagnostic challenge. METHODS: We used 3674 wound photographs from three specialised wound centres with the four most common types of foot and leg ulcers and the rare inflammatory differential diagnosis PG. The convolutional neural network classifier ConvNeXt 'B' was pretrained on LAION2B, ImageNet12k and ImageNet 1k before being trained and fine-tuned on an 85:15 train, validation split. RESULTS: The model achieved an overall high accuracy in multiclass classification of the chronic wounds (unbalanced accuracy 90%, balanced accuracy 87%). The sensitivity for identifying PG was 94%, while the sensitivity forother chronic wound types was 97% for diabetic foot ulcers (DFU), 92% for venous leg ulcers (VLU), 78% for mixed leg ulcers and 74% for arterial leg ulcers. DISCUSSION: The machine learning model effectively differentiates PG from the most common leg and foot ulcers and was very accurate for classifying DFU and VLU. A higher rate of misclassifications occurred for the other vascular ulcers, that is, mixed and arterial leg ulcers. This aligns with the challenges in clinical practice. CONCLUSION: Despite the limited number of wound images, this novel multiclass wound classification model accurately identified PG and differentiated leg and foot ulcer subtypes, providing a foundation for a diagnostic support system.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Simulation or modeling · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.644
Threshold uncertainty score0.786

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.031
GPT teacher head0.405
Teacher spread0.374 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it