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Record W4415058333 · doi:10.1002/agm2.70042

Dose–Response Associations of Grip Strength and Gait Speed With Multidimensional Mental Health

2025· article· en· W4415058333 on OpenAlexaboutno aff
Jiapei Wei, Liming Zhang, Shengyi Li, Xucheng Wu, Xingqi Cao, Liying Chen, Zuyun Liu, Yangzhen Lu, Xuan Ge

Bibliographic record

VenueAging Medicine · 2025
Typearticle
Languageen
FieldHealth Professions
TopicBalance, Gait, and Falls Prevention
Canadian institutionsnot available
FundersNational Natural Science Foundation of ChinaZhejiang UniversityMilstein Medical Asian American Partnership FoundationHarvard University
KeywordsGrip strengthMental healthGaitSample (material)Muscle strengthRange (aeronautics)

Abstract

fetched live from OpenAlex

ABSTRACT Objectives We aimed to examine the dose–response associations of grip strength and gait speed with multidimensional mental health among Chinese adults. Methods Cross‐sectional data on 661 adults from the ZheJiang longitudinal Study of Healthy Aging (JASHA) were utilized. Grip strength and gait speed were measured during physical examinations. Multidimensional mental health, covering cognitive function (the Auditory Verbal Learning Test (AVLT), the Montreal Cognitive Assessment (MoCA) test, and the Digit Symbol Substitution Test (DSST)), depressive symptoms (the Center for Epidemiologic Studies Depression (CES‐D) Scale), and psychological distress (the Perceived Stress Scale (PSS)), were assessed via standard questionnaires. Multivariable linear regression models and restricted cubic splines were applied to examine these associations. Results We found linear dose–response associations of grip strength and gait speed with most dimensions of mental health. For instance, higher grip strength was positively associated with higher cognitive function scores (AVLT_N3: β = 0.084, standard error (SE) = 0.032; DSST: β = 0.246, SE = 0.073 for per unit increase in grip strength) and lower CES‐D scores ( β = −1.265, SE = 0.626). Similarly, higher gait speed was associated with higher cognitive function scores (AVLT_N3: β = 2.882, SE = 0.860; MoCA: β = 0.996, SE = 0.499 for per unit increase in gait speed), lower CES‐D scores ( β = −1.448, SE = 0.692), and lower PSS scores ( β = −2.808, SE = 0.938). Notably, the associations were more pronounced in females and older adults. Conclusions In this sample spanning a wide range of ages, we found linear significant associations of grip strength and gait speed with most dimensions of mental health. The finding unveils the intrinsic connections between musculoskeletal function and mental health, highlighting the potential of preserving musculoskeletal function, such as via maintaining regular physical exercise, to prevent mental health disorders, especially for females and older adults.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.002
metaresearch head score (Gemma)0.003
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.004
Threshold uncertainty score0.009

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0020.003
Meta-epidemiology (narrow)0.0010.000
Meta-epidemiology (broad)0.0000.001
Bibliometrics0.0010.001
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0010.000
Insufficient payload (model declined to judge)0.0030.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.025
GPT teacher head0.384
Teacher spread0.359 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations2
Published2025
Admission routes1
Has abstractyes

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