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Record W4415058333 · doi:10.1002/agm2.70042

Dose–Response Associations of Grip Strength and Gait Speed With Multidimensional Mental Health

2025· article· en· W4415058333 on OpenAlex

Why this work is in the frame

A frame that forgets how it found something cannot be audited. These are the routes that admitted this work.

aboutThe title or abstract carries a Canadian signal from the geographic lexicon.
no affNo Canadian affiliation: this work is invisible to an affiliation-only frame.
No Canadian affiliation. An affiliation-only frame, the usual design, would never have seen this work. It is one of the works that make the case for inverting the frame.

Bibliographic record

VenueAging Medicine · 2025
Typearticle
Languageen
FieldHealth Professions
TopicBalance, Gait, and Falls Prevention
Canadian institutionsnot available
FundersNational Natural Science Foundation of ChinaZhejiang UniversityMilstein Medical Asian American Partnership FoundationHarvard University
KeywordsGrip strengthMental healthGaitSample (material)Muscle strengthRange (aeronautics)

Abstract

fetched live from OpenAlex

ABSTRACT Objectives We aimed to examine the dose–response associations of grip strength and gait speed with multidimensional mental health among Chinese adults. Methods Cross‐sectional data on 661 adults from the ZheJiang longitudinal Study of Healthy Aging (JASHA) were utilized. Grip strength and gait speed were measured during physical examinations. Multidimensional mental health, covering cognitive function (the Auditory Verbal Learning Test (AVLT), the Montreal Cognitive Assessment (MoCA) test, and the Digit Symbol Substitution Test (DSST)), depressive symptoms (the Center for Epidemiologic Studies Depression (CES‐D) Scale), and psychological distress (the Perceived Stress Scale (PSS)), were assessed via standard questionnaires. Multivariable linear regression models and restricted cubic splines were applied to examine these associations. Results We found linear dose–response associations of grip strength and gait speed with most dimensions of mental health. For instance, higher grip strength was positively associated with higher cognitive function scores (AVLT_N3: β = 0.084, standard error (SE) = 0.032; DSST: β = 0.246, SE = 0.073 for per unit increase in grip strength) and lower CES‐D scores ( β = −1.265, SE = 0.626). Similarly, higher gait speed was associated with higher cognitive function scores (AVLT_N3: β = 2.882, SE = 0.860; MoCA: β = 0.996, SE = 0.499 for per unit increase in gait speed), lower CES‐D scores ( β = −1.448, SE = 0.692), and lower PSS scores ( β = −2.808, SE = 0.938). Notably, the associations were more pronounced in females and older adults. Conclusions In this sample spanning a wide range of ages, we found linear significant associations of grip strength and gait speed with most dimensions of mental health. The finding unveils the intrinsic connections between musculoskeletal function and mental health, highlighting the potential of preserving musculoskeletal function, such as via maintaining regular physical exercise, to prevent mental health disorders, especially for females and older adults.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.242
Threshold uncertainty score0.349

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0010.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.025
GPT teacher head0.384
Teacher spread0.359 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it