MétaCan
Menu
Back to cohort

Prevalence and pathomorphological features of canine mast cell tumors

2025· article· W4415759398 on OpenAlex

Why this work is in the frame

A frame that forgets how it found something cannot be audited. These are the routes that admitted this work.

aboutThe title or abstract carries a Canadian signal from the geographic lexicon.
no affNo Canadian affiliation: this work is invisible to an affiliation-only frame.
No Canadian affiliation. An affiliation-only frame, the usual design, would never have seen this work. It is one of the works that make the case for inverting the frame.

Bibliographic record

VenueInternational Journal of Advanced Biochemistry Research · 2025
Typearticle
Language
FieldMedicine
TopicVeterinary Oncology Research
Canadian institutionsnot available
Fundersnot available
KeywordsGrading (engineering)HistopathologyMast cellPleomorphism (cytology)AnaplasiaPopulationTrunk

Abstract

fetched live from OpenAlex

Canine mast cell tumors are among the most common cutaneous neoplasms in dogs, with variable clinical behavior ranging from benign to highly aggressive forms. This study investigated the prevalence and pathomorphological features of mast cell tumors in 42 dogs diagnosed over a seven-month period. Tumor occurrence, clinical presentation, tumor location, cytological characteristics, and histopathological grading were analyzed. The age of occurrence of mast cell tumors ranged from 2 to 14 years, with the highest incidence in age group of 8 to 10 years and lowest incidence in age group of 12 to 14 years, with a mean age of 7.81 years, with a male predominance. Non-descript breeds were the most commonly affected, followed by Labrador and Golden Retrievers. The trunk was the most frequent tumor site. Cytological evaluation revealed characteristic round-to-oval mast cells with metachromatic granules and varying degrees of pleomorphism and anisokaryosis. Infiltration by eosinophils and neutrophils was frequently observed. Histopathological evaluation provided further characterization and grading of the tumors, using two widely accepted systems: Patnaik three-tier classification and the Kiupel two-tier system. Histopathology using Patnaik grading identified Grade II tumors as the most prevalent, while Kiupel grading showed an equal distribution of low-and high-grade tumors. These findings provide essential baseline data for improved diagnostic and therapeutic strategies in canine Mast cell tumors.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.003
metaresearch head score (Gemma)0.004
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesMeta-epidemiology (narrow), Research integrity
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Bench or experimental · Consensus signal: Bench or experimental
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.076
Threshold uncertainty score1.000

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0030.004
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0010.000
Bibliometrics0.0010.001
Science and technology studies0.0000.002
Scholarly communication0.0000.000
Open science0.0010.001
Research integrity0.0000.003
Insufficient payload (model declined to judge)0.0010.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.036
GPT teacher head0.428
Teacher spread0.391 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it