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Record W4416300709 · doi:10.1017/rsm.2025.10056

Impact of matrix-construction assumptions on quantitative overlap assessment in overviews: A meta-research study

2025· article· en· W4416300709 on OpenAlexaff
Javier Bracchiglione, Nicolás Meza, Dawid Pieper, Carole Lunny, Manuel Vargas-Peirano, Johanna Vicuña, Fernando Briceño Muga, Roberto Garnham Parra, Ignacio Carrasco, Gerard Urrútia, Xavier Bonfill, Eva Madrid

Bibliographic record

VenueResearch Synthesis Methods · 2025
Typearticle
Languageen
FieldDecision Sciences
TopicMeta-analysis and systematic reviews
Canadian institutionsUniversity of British ColumbiaMD Precision (Canada)St. Michael's Hospital
FundersUniversitat Autònoma de Barcelona
KeywordsPairwise comparisonMetric (unit)GuidelineSelection (genetic algorithm)Evaluation methodsMatrix (chemical analysis)Sample size determination

Abstract

fetched live from OpenAlex

Overlap of primary studies among multiple systematic reviews (SRs) is a major challenge when conducting overviews. The corrected covered area (CCA) is a metric computed from a matrix of evidence that quantifies overlap. Therefore, the assumptions used to generate the matrix may significantly affect the CCA. We aim to explore how these varying assumptions influence CCA calculations. We searched two databases for intervention-focused overviews published during 2023. Two reviewers conducted study selection and data extraction. We extracted overview characteristics and methods to handle overlap. For seven sampled overviews, we calculated overall and pairwise CCA across 16 scenarios, representing four matrix-construction assumptions. Of 193 included overviews, only 23 (11.9%) adhered to an overview-specific reporting guideline (e.g. PRIOR). Eighty-five (44.0%) did not address overlap; 14 (7.3%) only mentioned it in the discussion; and 94 (48.7%) incorporated it into methods or results (38 using CCA). Among the seven sampled overviews, CCA values varied depending on matrix-construction assumptions, ranging from 1.2% to 13.5% with the overall method and 0.0% to 15.7% with the pairwise method. CCA values may vary depending on the assumptions made during matrix construction, including scope, treatment of structural missingness, and handling of publication threads. This variability calls into question the uncritical use of current CCA thresholds and underscores the need for overview authors to report both overall and pairwise CCA calculations. Our preliminary guidance for transparently reporting matrix-construction assumptions may improve the accuracy and reproducibility of CCA assessments.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.751
metaresearch head score (Gemma)0.914
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesMetaresearch
Consensus categoriesMetaresearch
DomainCandidate signal: Methods · Consensus signal: Methods
Study designCandidate signal: Simulation or modeling · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: none
Teacher disagreement score0.249
Threshold uncertainty score0.307

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.7510.914
Meta-epidemiology (narrow)0.0050.005
Meta-epidemiology (broad)0.0100.029
Bibliometrics0.0170.024
Science and technology studies0.0040.010
Scholarly communication0.0140.016
Open science0.0090.016
Research integrity0.0060.007
Insufficient payload (model declined to judge)0.0070.001

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.955
GPT teacher head0.801
Teacher spread0.153 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; the direct Gemma label and the distilled Codex classifier agree on what is shown here.

Study designSimulation or modeling
DomainMethods
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2025
Admission routes1
Has abstractyes

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