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Record W4416940269 · doi:10.1016/j.imu.2025.101720

SuSastho.AI: A multimodal medical copilot for adolescents using evidence-based medicine and large language models

2025· article· en· W4416940269 on OpenAlex

Why this work is in the frame

A frame that forgets how it found something cannot be audited. These are the routes that admitted this work.

fundA Canadian funder is recorded on the work.
no affNo Canadian affiliation: this work is invisible to an affiliation-only frame.
No Canadian affiliation. An affiliation-only frame, the usual design, would never have seen this work. It is one of the works that make the case for inverting the frame.

Bibliographic record

VenueInformatics in Medicine Unlocked · 2025
Typearticle
Languageen
FieldComputer Science
TopicTopic Modeling
Canadian institutionsnot available
FundersInternational Development Research CentreUnited International UniversityBill and Melinda Gates Foundation
KeywordsMental healthCorrectnessHealth careUnintended consequencesMental healthcareReproductive healthFace (sociological concept)Occupational safety and healthHealth equity

Abstract

fetched live from OpenAlex

Adolescents in Bangladesh face serious sexual, reproductive, and mental health challenges due to cultural stigma, poverty, and limited healthcare infrastructure. Within the country, 63% of adolescents are deprived of essential sexual and reproductive health services, and only 13% receive mental health support. Adolescents living in urban slums and with disabilities face additional challenges in receiving reliable health information. This limited access exposes them to a high risk of sexually transmitted infections (STIs), unintended pregnancies, and serious mental health issues. Addressing these challenges, our study introduces SuSastho.AI, a healthcare copilot providing access to reliable health information to adolescents. We utilized large language models, along with Evidence-Based Medicine, retrieval-augmented generation, and a clinically validated dataset to provide evidence-based responses, supporting both voice and text-based interactions. Clinical evaluation of a pilot study shows our method reduces incorrect responses by 26.9% and increases response correctness by 16.1% compared to other methods. It achieved an accuracy rate of 86.7% when specifically evaluated based on available knowledge. While the responses are mostly consistent with up-to-date medical practices, occasional, less precise responses highlight the need for further refinement. Participants reported overall positive feedback, where 87% found answers to their questions, and 90.7% found responses relevant. Our results show that SuSastho.AI can provide reliable and evidence-based information while being an affordable way to support traditional healthcare systems with a high potential to transform digital health. The study sets an example as an evidence-based healthcare copilot to support adolescents and lays the foundation for future research where evidence-based tools overcome social barriers.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.003
metaresearch head score (Gemma)0.002
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Simulation or modeling · Consensus signal: none
GenreCandidate signal: Methods · Consensus signal: none
Teacher disagreement score0.930
Threshold uncertainty score0.836

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0030.002
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0010.000
Bibliometrics0.0010.001
Science and technology studies0.0000.000
Scholarly communication0.0000.001
Open science0.0010.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.068
GPT teacher head0.371
Teacher spread0.303 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it