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Almonds, Glycemic Index, Dietary Antioxidants and Risk Factors for Coronary Heart Disease

2006· article· en· W6066670 on OpenAlex

Why this work is in the frame

A frame that forgets how it found something cannot be audited. These are the routes that admitted this work.

affAt least one author lists a Canadian institution in the pinned OpenAlex snapshot.

Bibliographic record

VenueThe FASEB Journal · 2006
Typearticle
Languageen
FieldNursing
TopicNuts composition and effects
Canadian institutionsSt. Michael's HospitalUniversity of Toronto
FundersAlmond Board of California
KeywordsPostprandialGlycemic indexGlycemicGlycemic loadMedicineMealOxidative stressDiabetes mellitusFood scienceInsulinInternal medicineEndocrinologyChemistry

Abstract

fetched live from OpenAlex

Background Low glycemic index (GI) diets may be of benefit in reducing risk of coronary heart disease (CHD) and diabetes, possibly by reducing postprandial glucose, insulin and oxidative stress. Objective To assess whether almonds reduce the glycemic response, insulinemia, and oxidative stress more than the same reduction by a low GI food (parboiled rice) without endogenous antioxidants. Methods Two studies were undertaken. The first study (n=10) assessed the dose‐response effect of almonds in reducing postprandial glycemia. The second study (n=15) assessed a high GI meal (mashed potatoes) compared to two low GI meals (parboiled rice, almonds) on postprandial glucose, insulin and measures of oxidative stress. All meals contained 50g available carbohydrates and were balanced for protein and fat. Results The first study found that 60g almonds significantly reduced the glycemic response of white bread. In the second study, the glycemic responses (mean±SE) of the low GI almond (54.5±6.9, P<0.001) and rice (37.5±6.3, P<0.001) meals were significantly reduced compared to white bread, while the high GI potato (94.3±11.1, P=0.61) meal showed no significant difference. Insulin values reflected the glycemic responses. Protein thiols tended to be higher following the almond meal indicating less oxidative damage. Conclusion Low GI foods lower postprandial glycemic and insulinemic response curves, and tend to reduce oxidative stress. Preliminary data indicate that low GI foods as part of a healthy diet may reduce risk factors for CHD and diabetes. Support: Almond Board of California

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.122
Threshold uncertainty score0.528

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0010.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.014
GPT teacher head0.253
Teacher spread0.239 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it