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Record W6982402744

The Impact of Frailty on Functional Survival in Patients 1-Year Post-Cardiac Surgery

2015· other· en· W6982402744 on OpenAlex

Why this work is in the frame

A frame that forgets how it found something cannot be audited. These are the routes that admitted this work.

aboutThe title or abstract carries a Canadian signal from the geographic lexicon.
no affNo Canadian affiliation: this work is invisible to an affiliation-only frame.
No Canadian affiliation. An affiliation-only frame, the usual design, would never have seen this work. It is one of the works that make the case for inverting the frame.

Bibliographic record

VenueMspace (University of Manitoba) · 2015
Typeother
Languageen
FieldBiochemistry, Genetics and Molecular Biology
TopicMachine Learning in Bioinformatics
Canadian institutionsnot available
Fundersnot available
KeywordsDeliriumCardiac surgeryEuroSCORERisk assessmentAdverse effectRisk factorVulnerability (computing)Frailty syndromeMEDLINE
DOInot available

Abstract

fetched live from OpenAlex

Frailty is an emerging concept in medicine yet to be adequately explored as a risk factor in cardiac surgery. Frailty is a geriatric syndrome of decreased physiologic reserves and increased vulnerability to stressors. It may be a strong predictor of adverse events following cardiac surgery such as post-operative delirium. Given that elderly patients are increasingly referred for cardiac surgery, the prevalence of frailty amongst this group is on the rise. Risk prediction, not just for mortality but also morbidity is pivotal in order to determine the optimal timing and selection for this increasingly complex group of patients. However, currently available risk scores (i.e. Euroscore II, Society of Thoracic Surgery) fail to account for the patient’s total physiologic reserves that will be called upon at the time of surgery. We have previously identified that, when using detailed frailty assessment tools, ~55% of elective cardiac surgery patients in Manitoba can be deemed frail. Preoperative frailty was associated with a 5-8-fold increase in the occurrence of postoperative delirium and prolonged hospital length of stay. While these represent important and novel findings, there is a pressing need to understand the longer-term impact of frailty before it can be integrated into current cardiac surgery risk scores. The study objective, therefore is to examine the mid- and long-term impact of frailty, with and without the co-occurrence of delirium, on outcomes following cardiac surgery. We ultimately aim to understand how incorporation of frailty assessment impact patient well-being in elderly patients undergoing cardiac surgery.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.522
Threshold uncertainty score0.781

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.012
GPT teacher head0.215
Teacher spread0.202 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it