The roles of cellular Factor XIII-A in osteoblasts
Bibliographic record
Abstract
Bone 10 Bone matrix and mineralization 11 Collagen type I 12 Biosynthesis and secretion of collagen type I 12 Microtubule dynamics and post-translational modifications of tubulin 14 Plasma membrane and cell surface tubulin 18 Caveolae 19 Structure and functions 19 Caveolin and bone 21 Src and its role on bone formation 22 Caveolin and c-Src 23 Role of caveolae in matrix turnover 24 Transglutaminases 25 Functions and TG substrates 25 TG isoform-specific substrate peptides 30 TG Inhibitors 32 Factor XIII-A 35 Factor XIII-A in bone and osteoblast 37 Rationale, hypothesis and objectives 38 References 41 Chapter 2-MC3T3-E1 cell lines as a cell culture model to study caveolae and plasma membrane tubulin in osteoblasts 53 Preparation of caveolae enriched fractions from MC3T3-E1 osteoblast 54 Plasma membrane tubulin in MC3T3-E1 osteoblasts 56 References 58 III Chapter 3-Detyrosinated Glu-tubulin is a substrate for cell surface Factor XIII-A in osteoblasts 59
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How this classification was reachedexpand
Full frame machine prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.
Distilled classifier scores by category (both heads)
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.000 | 0.000 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.000 | 0.000 |
| Bibliometrics | 0.000 | 0.000 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.000 | 0.000 |
| Insufficient payload (model declined to judge) | 0.001 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".