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Record W7108660306 · doi:10.5376/bm.2025.16.0029

Observation of Genetic Markers for Resistance to Gastrointestinal Parasites in Goats

2025· article· W7108660306 on OpenAlex

Why this work is in the frame

A frame that forgets how it found something cannot be audited. These are the routes that admitted this work.

venuePublished in a venue whose home country is Canada.
no affNo Canadian affiliation: this work is invisible to an affiliation-only frame.
No Canadian affiliation. An affiliation-only frame, the usual design, would never have seen this work. It is one of the works that make the case for inverting the frame.

Bibliographic record

VenueBioscience Methods · 2025
Typearticle
Language
FieldVeterinary
TopicHelminth infection and control
Canadian institutionsnot available
Fundersnot available
KeywordsResistance (ecology)GeneGenetic diversityEconomic shortageGenetic markerDewormingSingle-nucleotide polymorphismGenetic analysisMicrosatellite

Abstract

fetched live from OpenAlex

In many small-scale farmers and grazing systems, the biggest problem that goats face is not the shortage of feed, but the health risks and production losses caused by gastrointestinal parasites. Although such problems have long existed, they are now even more troublesome - the old method of relying on deworming drugs to solve them is becoming less and less effective at present. On the one hand, drug resistance is intensifying; on the other hand, the pressure of environmental protection and sustainability also forces people to rethink their strategies. This study systematically explored the genetic basis of goat resistance to parasites, with a focus on analyzing key genetic markers related to immune response, intestinal barrier function, and inflammatory regulation. It also reviewed the application progress of different types of markers such as microsatellites (SSR), single nucleotide polymorphisms (SNPS), and candidate genes in resistance research. And strategies such as QTL mapping, genome-wide association analysis (GWAS), and gene expression analysis were evaluated. Through case comparisons of breeds such as Boer goats, native goats, Indian Jamunapari and African Red Maasai, this study reveals the diversity of resistance genes among breeds and their specific characteristics. This study emphasizes the significance of strengthening multi-group joint analysis and data sharing, providing a theoretical basis for building an ecological and sustainable goat anti-parasitic breeding system.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.004
metaresearch head score (Gemma)0.007
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesMeta-epidemiology (narrow)
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: none
GenreCandidate signal: Methods · Consensus signal: Methods
Teacher disagreement score0.781
Threshold uncertainty score1.000

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0040.007
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0010.002
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.092
GPT teacher head0.442
Teacher spread0.350 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it