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Record W7116867654 · doi:10.1016/j.avb.2025.102125

The link between psychosis, negative affect, and violence: A systematic review

2025· article· en· W7116867654 on OpenAlex

Why this work is in the frame

A frame that forgets how it found something cannot be audited. These are the routes that admitted this work.

affAt least one author lists a Canadian institution in the pinned OpenAlex snapshot.

Bibliographic record

VenueAggression and Violent Behavior · 2025
Typearticle
Languageen
FieldPsychology
TopicPsychopathy, Forensic Psychiatry, Sexual Offending
Canadian institutionsMcMaster UniversitySimon Fraser University
Fundersnot available
KeywordsLink (geometry)Poison controlHuman factors and ergonomicsInjury preventionSuicide prevention

Abstract

fetched live from OpenAlex

A moderate positive association has consistently been observed between psychosis and violence in existing literature. However, substantial variation is present across individual studies, and there is preliminary support for negative affect (i.e., anger, hostility, anxiety) as a causal link between these two constructs to explain the heterogeneity of results. Due to the limited scope of previous reviews and relevant studies published since, a systematic review of 35 empirical studies ( N = 15,597) was conducted to examine if, across existing literature that includes all three constructs, negative affect may correlate or mediate the preestablished relationship between psychosis diagnosis and/or symptoms and violence. Anger or hostility was positively associated with violence or physical aggression for individuals with a diagnosis and/or symptoms of psychosis in 31 (89 %) of the studies, of which seven were cross-sectional, nine were retrospectively predictive, and 19 were prospective. Anger which followed positive psychosis symptoms played a positive statistically mediating role in participants' subsequent violence in all six studies that investigated this pathway. Within studies that examined other forms of negative affect (anxiety, depression, fear), nine discovered positive association with violence, six found negative association, and seven demonstrated no association. These results align with theoretical models of violence in individuals with psychosis, suggesting that psychosis is a sometimes necessary but often insufficient risk factor for violence. When assessing violence risk for individuals with psychosis, negative affect may be critical to consider alongside symptoms in case formulation and to target in subsequent intervention efforts, as opposed to symptoms in isolation.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Systematic review · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: none
Teacher disagreement score0.729
Threshold uncertainty score0.917

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0010.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0010.000
Bibliometrics0.0000.000
Science and technology studies0.0010.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.021
GPT teacher head0.369
Teacher spread0.348 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it