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Clostridioides difficile and rotavirus outbreak in an acute care unit in Alberta, Canada

2025· article· W7128597824 on OpenAlex

Why this work is in the frame

A frame that forgets how it found something cannot be audited. These are the routes that admitted this work.

venuePublished in a venue whose home country is Canada.
aboutThe title or abstract carries a Canadian signal from the geographic lexicon.
no affNo Canadian affiliation: this work is invisible to an affiliation-only frame.
No Canadian affiliation. An affiliation-only frame, the usual design, would never have seen this work. It is one of the works that make the case for inverting the frame.

Bibliographic record

VenueCanadian Journal of Infection Control · 2025
Typearticle
Language
FieldMedicine
TopicClostridium difficile and Clostridium perfringens research
Canadian institutionsnot available
Fundersnot available
KeywordsOutbreakRotavirusClostridioidesInfection controlAuditPsychological interventionDiarrheaTransmission (telecommunications)

Abstract

fetched live from OpenAlex

Background: Rotavirus is a commonly recognized cause of gastrointestinal illness in infants and young children. It is an under-appreciated cause of gastroenteritis in adult patients. Clostridioides (formerly Clostridium) difficile is the most important infectious cause of antibiotic-associated diarrhea worldwide. A mixed infection outbreak involving rotavirus and Clostridioides difficile has not been fully characterized. Methods: This report highlights a mixed outbreak of Clostridioides difficile infection (CDI) and rotavirus among adult patients in a community hospital in Alberta, Canada, and describes the interventions implemented. Results: On March 20, a CDI outbreak was declared following five cases of hospital-acquired CDI, and on March 25, one patient was identified with a co-infection. A mixed pathogen outbreak was then declared after three new cases of rotavirus were detected on the same unit. Infection prevention and control (IPAC) measures were implemented in accordance with local IPAC guidelines. In addition, hand hygiene, environmental cleaning, and fluorescent marker audits were conducted. A hand hygiene audit of 21 opportunities revealed 66.7% compliance. Fluorescent marker audits showed improper cleaning of patient environments and shared equipment. The ward received targeted education and enhanced cleaning based on audit findings. The rotavirus and CDI outbreaks were declared over on April 2 and April 10, respectively. Conclusion: Considering that rotavirus is an under-recognized cause of gastrointestinal disease in adults, awareness of this pathogen as a potential cause of an outbreak is important to prompt early testing and ensure appropriate infection control interventions to prevent its spread.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.001
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesMeta-epidemiology (narrow)
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.044
Threshold uncertainty score1.000

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0010.001
Meta-epidemiology (narrow)0.0010.001
Meta-epidemiology (broad)0.0010.000
Bibliometrics0.0030.002
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.002
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.011
GPT teacher head0.276
Teacher spread0.265 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it