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Clostridioides difficile and rotavirus outbreak in an acute care unit in Alberta, Canada

2025· article· W7128597824 on OpenAlexvenueaboutno aff
Carmen Tse, Tonya Carson, Ashley Shackleford, Infection Prevention and Control, Covenant Health, Edmonton, AB, Canada, Erin L. Roberts, Conar O’Neil, Molly Lin

Bibliographic record

VenueCanadian Journal of Infection Control · 2025
Typearticle
Language
FieldMedicine
TopicClostridium difficile and Clostridium perfringens research
Canadian institutionsnot available
Fundersnot available
KeywordsOutbreakRotavirusClostridioidesInfection controlAuditPsychological interventionDiarrheaTransmission (telecommunications)

Abstract

fetched live from OpenAlex

Background: Rotavirus is a commonly recognized cause of gastrointestinal illness in infants and young children. It is an under-appreciated cause of gastroenteritis in adult patients. Clostridioides (formerly Clostridium) difficile is the most important infectious cause of antibiotic-associated diarrhea worldwide. A mixed infection outbreak involving rotavirus and Clostridioides difficile has not been fully characterized. Methods: This report highlights a mixed outbreak of Clostridioides difficile infection (CDI) and rotavirus among adult patients in a community hospital in Alberta, Canada, and describes the interventions implemented. Results: On March 20, a CDI outbreak was declared following five cases of hospital-acquired CDI, and on March 25, one patient was identified with a co-infection. A mixed pathogen outbreak was then declared after three new cases of rotavirus were detected on the same unit. Infection prevention and control (IPAC) measures were implemented in accordance with local IPAC guidelines. In addition, hand hygiene, environmental cleaning, and fluorescent marker audits were conducted. A hand hygiene audit of 21 opportunities revealed 66.7% compliance. Fluorescent marker audits showed improper cleaning of patient environments and shared equipment. The ward received targeted education and enhanced cleaning based on audit findings. The rotavirus and CDI outbreaks were declared over on April 2 and April 10, respectively. Conclusion: Considering that rotavirus is an under-recognized cause of gastrointestinal disease in adults, awareness of this pathogen as a potential cause of an outbreak is important to prompt early testing and ensure appropriate infection control interventions to prevent its spread.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.001
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.041
Threshold uncertainty score0.297

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0010.001
Meta-epidemiology (narrow)0.0010.001
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0010.002
Science and technology studies0.0060.001
Scholarly communication0.0010.000
Open science0.0010.001
Research integrity0.0010.001
Insufficient payload (model declined to judge)0.0020.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.011
GPT teacher head0.276
Teacher spread0.265 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2025
Admission routes2
Has abstractyes

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