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Application of quantitative electroencephalography in digital screening for mild cognitive impairment

2025· article· zh· W7162865957 on OpenAlex

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aboutThe title or abstract carries a Canadian signal from the geographic lexicon.
no affNo Canadian affiliation: this work is invisible to an affiliation-only frame.
No Canadian affiliation. An affiliation-only frame, the usual design, would never have seen this work. It is one of the works that make the case for inverting the frame.

Bibliographic record

VenueDOAJ (DOAJ: Directory of Open Access Journals) · 2025
Typearticle
Languagezh
FieldPsychology
TopicCognitive Functions and Memory
Canadian institutionsnot available
Fundersnot available
KeywordsElectroencephalographyRecallPrefrontal cortexCognitive impairmentReceiver operating characteristicCognition

Abstract

fetched live from OpenAlex

Objective To explore the quantitative electroencephalography (qEEG) characteristics of the prefrontal cortex in patients with mild cognitive impairment (MCI) during digital screening tasks for MCI screening. Methods A total of 592 MCI patients (MCI group) and 317 normal cognitively elderly individuals (control group) were recruited from 40 communities in Nanjing, Jiangsu Province, from July to August, 2024. All participants were assessed using Montreal Cognitive Assessment-Beijing Version (MoCA-BJ). Prefrontal EEG data were collected using a portable EEG device, and power spectral analysis was performed via Fast Fourier Transform. An XG-Boost algorithm was employed to construct an MCI identification model based on qEEG power features, and the model's performance was evaluated using receiver operating characteristic (ROC) curve. Results Compared with the control group, prefrontal δ, α, and β band power increased during screening tasks in MCI group (P<0.05); δ power was negatively correlated with MoCA-BJ total scores, and visuospatial/executive function, attention and delayed recall scores (r=-0.269, -0.169, -0.133, -0.171, P<0.001); α power was negatively correlated with MoCA-BJ total scores, attention and delayed recall scores (r=-0.113, -0.075, -0.091, P<0.05). The XGBoost model based on δ and α power was excellent in MCI identification, with an area under the curve of 0.91, accuracy of 0.81, precision of 0.89, F1 score of 0.84, recall of 0.80, and specificity of 0.81. Conclusion MCI patients exhibit increased power in the prefrontal δ and α frequency bands during digital screening tasks, which is associated with cognitive decline. An XGBoost model based on qEEG power features can enable early prediction of MCI.

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Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.002
metaresearch head score (Gemma)0.001
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesMeta-epidemiology (narrow), Insufficient payload (model declined to judge)
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.321
Threshold uncertainty score1.000

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0020.001
Meta-epidemiology (narrow)0.0000.001
Meta-epidemiology (broad)0.0010.001
Bibliometrics0.0030.003
Science and technology studies0.0000.000
Scholarly communication0.0010.002
Open science0.0010.000
Research integrity0.0000.001
Insufficient payload (model declined to judge)0.0010.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.206
GPT teacher head0.569
Teacher spread0.363 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it