6,013
citations
Works
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484 workspage 1 of 20
Neuronal α-Synucleinopathy with Severe Movement Disorder in Mice Expressing A53T Human α-Synuclein
2002· article· en· Neuron· Medicine
fundno affno abstract
1,259
citations
Trehalose, a Novel mTOR-independent Autophagy Enhancer, Accelerates the Clearance of Mutant Huntingtin and α-Synuclein
2006· article· en· Journal of Biological Chemistry· Medicine
fundno aff
1,125
citations
Sensitivity of secondary structure propensities to sequence differences between α‐ and γ‐synuclein: Implications for fibrillation
2006· article· en· Protein Science· Medicine
afffund
742
citations
Alpha-synuclein in Parkinson’s disease and other synucleinopathies: from overt neurodegeneration back to early synaptic dysfunction
2023· review· en· Cell Death and Disease· Medicine
fundno aff
739
citations
Alpha‐synuclein p.H50Q, a novel pathogenic mutation for Parkinson's disease
2013· article· en· Movement Disorders· Medicine
afffund
662
citations
α-Synuclein and tau concentrations in cerebrospinal fluid of patients presenting with parkinsonism: a cohort study
2011· article· en· The Lancet Neurology· Medicine
affno abstract
629
citations
Alpha‐synuclein <scp>RT</scp>‐Qu<scp>IC</scp> in the <scp>CSF</scp> of patients with alpha‐synucleinopathies
2016· article· en· Annals of Clinical and Translational Neurology· Medicine
fundno aff
613
citations
α-Synuclein Membrane Interactions and Lipid Specificity
2000· article· en· Journal of Biological Chemistry· Medicine
afffund
608
citations
REM sleep behaviour disorder
2018· review· en· Nature Reviews Disease Primers· Neuroscience
affno abstract
487
citations
Poly(ADP-ribose) drives pathologic α-synuclein neurodegeneration in Parkinson’s disease
2018· article· en· Science· Medicine
aff
465
citations
Induction of α-Synuclein Aggregation by Intracellular Nitrative Insult
2001· article· en· Journal of Neuroscience· Medicine
fundno aff
442
citations
Implication of Alpha-Synuclein Phosphorylation at S129 in Synucleinopathies: What Have We Learned in the Last Decade?
2016· review· en· Journal of Parkinson s Disease· Medicine
afffund
425
citations
356
citations
Abberant α-Synuclein Confers Toxicity to Neurons in Part through Inhibition of Chaperone-Mediated Autophagy
2009· article· en· PLoS ONE· Medicine
afffund
347
citations
C-terminal calcium binding of α-synuclein modulates synaptic vesicle interaction
2018· article· en· Nature Communications· Medicine
aff
335
citations
Detection of α-synuclein in CSF by RT-QuIC in patients with isolated rapid-eye-movement sleep behaviour disorder: a longitudinal observational study
2021· article· en· The Lancet Neurology· Medicine
fundno affno abstract
332
citations
α-Synuclein strains target distinct brain regions and cell types
2019· article· en· Nature Neuroscience· Biochemistry, Genetics and Molecular Biology
affno abstract
329
citations
CNS expression of glucocerebrosidase corrects α-synuclein pathology and memory in a mouse model of Gaucher-related synucleinopathy
2011· article· en· Proceedings of the National Academy of Sciences· Medicine
aff
317
citations
Acid β‐glucosidase mutants linked to gaucher disease, parkinson disease, and lewy body dementia alter α‐synuclein processing
2011· article· en· Annals of Neurology· Medicine
aff
305
citations
α‐Synuclein oligomers and clinical implications for Parkinson disease
2012· review· en· Annals of Neurology· Medicine
afffund
291
citations
Cathepsin D expression level affects alpha-synuclein processing, aggregation, and toxicity in vivo
2009· article· en· Molecular Brain· Medicine
afffund
281
citations
The prion hypothesis in Parkinson's disease: Braak to the future
2013· review· en· Acta Neuropathologica Communications· Biochemistry, Genetics and Molecular Biology
aff
272
citations
GATA transcription factors directly regulate the Parkinson's disease-linked gene α-synuclein
2008· article· en· Proceedings of the National Academy of Sciences· Medicine
aff
268
citations
Interface between tauopathies and synucleinopathies: A tale of two proteins
2006· review· en· Annals of Neurology· Medicine
aff
264
citations