Patterns of genomic loss of heterozygosity predict homologous recombination repair defects in epithelial ovarian cancer
2012· article· en· British Journal of Cancer· Medicine
aff
852
citations
Works
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Mutations in SUFU predispose to medulloblastoma
2002· article· en· Nature Genetics· Biochemistry, Genetics and Molecular Biology
affno abstract
799
citations
Integrative Molecular Characterization of Malignant Pleural Mesothelioma
2018· article· en· Cancer Discovery· Medicine
aff
618
citations
Genetic mechanisms of target antigen loss in CAR19 therapy of acute lymphoblastic leukemia
2018· article· en· Nature Medicine· Medicine
affno abstract
567
citations
The integrated landscape of driver genomic alterations in glioblastoma
2013· article· en· Nature Genetics· Biochemistry, Genetics and Molecular Biology
affno abstract
560
citations
A quantitative review of heterozygosity–fitness correlations in animal populations
2009· review· en· Molecular Ecology· Biochemistry, Genetics and Molecular Biology
aff
461
citations
TITAN: inference of copy number architectures in clonal cell populations from tumor whole-genome sequence data
2014· article· en· Genome Research· Biochemistry, Genetics and Molecular Biology
afffund
429
citations
Frequent somatic mutations in PTEN and TP53 are mutually exclusive in the stroma of breast carcinomas
2002· article· en· Nature Genetics· Biochemistry, Genetics and Molecular Biology
affno abstract
422
citations
‘Good genes as heterozygosity’: the major histocompatibility complex and mate choice in Atlantic salmon (Salmo salar)
2001· article· en· Proceedings of the Royal Society B Biological Sciences· Agricultural and Biological Sciences
afffund
372
citations
Evolutionary conservation of the clk-1-dependent mechanism of longevity: loss of mclk1 increases cellular fitness and lifespan in mice
2005· article· en· Genes & Development· Biochemistry, Genetics and Molecular Biology
afffund
347
citations
Tip60 is a haplo-insufficient tumour suppressor required for an oncogene-induced DNA damage response
2007· article· en· Nature· Biochemistry, Genetics and Molecular Biology
affno abstract
341
citations
<emph type="ital">DICER1</emph> Mutations in Familial Multinodular Goiter With and Without Ovarian Sertoli-Leydig Cell Tumors
2011· article· en· JAMA· Medicine
afffundabout
333
citations
Microsatellite DNA in peach (Prunus persicaL. Batsch) and its use in fingerprinting and testing the genetic origin of cultivars
2000· article· en· Genome· Biochemistry, Genetics and Molecular Biology
venueno aff
332
citations
A recurrent germline PAX5 mutation confers susceptibility to pre-B cell acute lymphoblastic leukemia
2013· article· en· Nature Genetics· Medicine
afffundno abstract
329
citations
Germline loss-of-function mutations in LZTR1 predispose to an inherited disorder of multiple schwannomas
2013· article· en· Nature Genetics· Medicine
affno abstract
322
citations
Age‐dependent genetic effects on a secondary sexual trait in male Alpine ibex,Capra ibex
2007· article· en· Molecular Ecology· Biochemistry, Genetics and Molecular Biology
afffund
313
citations
Whole-Genome Profiling of Pediatric Diffuse Intrinsic Pontine Gliomas Highlights Platelet-Derived Growth Factor Receptor α and Poly (ADP-ribose) Polymerase As Potential Therapeutic Targets
2010· article· en· Journal of Clinical Oncology· Medicine
afffund
313
citations
Fluorescence Visualization Detection of Field Alterations in Tumor Margins of Oral Cancer Patients
2006· article· en· Clinical Cancer Research· Dentistry
aff
311
citations
Deciphering the role of heterozygous mutations in genes associated with parkinsonism
2007· review· en· The Lancet Neurology· Medicine
affno abstract
311
citations
Integrative analysis of genome-wide loss of heterozygosity and monoallelic expression at nucleotide resolution reveals disrupted pathways in triple-negative breast cancer
2012· article· en· Genome Research· Biochemistry, Genetics and Molecular Biology
afffund
294
citations
Clinical, biochemical, and genetic characterization of a novel estrogen-dependent inherited form of angioedema
2000· article· en· Journal of Allergy and Clinical Immunology· Medicine
affno abstract
294
citations
Ovarian carcinomas with genetic and epigenetic BRCA1 loss have distinct molecular abnormalities
2008· article· en· BMC Cancer· Medicine
afffund
286
citations
Loss-of-heterozygosity analysis of small-cell lung carcinomas using single-nucleotide polymorphism arrays
2000· article· en· Nature Biotechnology· Biochemistry, Genetics and Molecular Biology
affno abstract
278
citations
Genetic etiology of oral cancer
2017· review· en· Oral Oncology· Biochemistry, Genetics and Molecular Biology
affno abstract
261
citations
Association Between Biallelic and Monoallelic Germline MYH Gene Mutations and Colorectal Cancer Risk
2004· article· en· JNCI Journal of the National Cancer Institute· Medicine
affabout
260
citations