Atenolol versus Losartan in Children and Young Adults with Marfan's Syndrome
2014· article· en· New England Journal of Medicine· Biochemistry, Genetics and Molecular Biology
aff
522
citations
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Vascular matrix remodeling in patients with bicuspid aortic valve malformations: implications for aortic dilatation
2003· article· en· Journal of Thoracic and Cardiovascular Surgery· Medicine
affno abstract
438
citations
The molecular genetics of Marfan syndrome and related disorders
2006· review· en· Journal of Medical Genetics· Biochemistry, Genetics and Molecular Biology
afffund
431
citations
Cellular and molecular mechanisms of thoracic aortic aneurysms
2009· review· en· Nature Reviews Cardiology· Biochemistry, Genetics and Molecular Biology
fundno affno abstract
332
citations
Consensus statement on surgical pathology of the aorta from the Society for Cardiovascular Pathology and the Association For European Cardiovascular Pathology: II. Noninflammatory degenerative diseases — nomenclature and diagnostic criteria
2016· review· en· Cardiovascular Pathology· Medicine
affno abstract
297
citations
Circulating Transforming Growth Factor-β in Marfan Syndrome
2009· article· en· Circulation· Biochemistry, Genetics and Molecular Biology
aff
270
citations
Results of surgery for aortic root aneurysm in patients with Marfan syndrome
2003· article· en· Journal of Thoracic and Cardiovascular Surgery· Medicine
affno abstract
241
citations
Mutations in Fibrillin-1 Cause Congenital Scleroderma: Stiff Skin Syndrome
2010· article· en· Science Translational Medicine· Medicine
afffund
240
citations
Loss of Elastic Fiber Integrity and Reduction of Vascular Smooth Muscle Contraction Resulting From the Upregulated Activities of Matrix Metalloproteinase-2 and -9 in the Thoracic Aortic Aneurysm in Marfan Syndrome
2007· article· en· Circulation Research· Biochemistry, Genetics and Molecular Biology
aff
236
citations
Rationale and design of a randomized clinical trial of β-blocker therapy (atenolol) versus angiotensin II receptor blocker therapy (losartan) in individuals with Marfan syndrome
2007· article· en· American Heart Journal· Biochemistry, Genetics and Molecular Biology
affno abstract
231
citations
Long-Term Doxycycline Is More Effective Than Atenolol to Prevent Thoracic Aortic Aneurysm in Marfan Syndrome Through the Inhibition of Matrix Metalloproteinase-2 and -9
2008· article· en· Circulation Research· Medicine
aff
220
citations
Canadian Cardiovascular Society 2009 Consensus Conference on the management of adults with congenital heart disease: Outflow tract obstruction, coarctation of the aorta, tetralogy of Fallot, Ebstein anomaly and Marfan's syndrome
2010· article· en· Canadian Journal of Cardiology· Medicine
affvenueaboutno abstract
210
citations
A quarter of a century of experience with aortic valve-sparing operations
2014· article· en· Journal of Thoracic and Cardiovascular Surgery· Medicine
affno abstract
196
citations
Long-term outcome in patients with Marfan syndrome: is aortic dissection the only cause of sudden death?
2003· article· en· Journal of the American College of Cardiology· Biochemistry, Genetics and Molecular Biology
affno abstract
195
citations
Results of aortic valve–sparing operations
2001· article· en· Journal of Thoracic and Cardiovascular Surgery· Medicine
affno abstract
192
citations
Reimplantation of the aortic valve at 20 years
2016· article· en· Journal of Thoracic and Cardiovascular Surgery· Medicine
affno abstract
180
citations
Usefulness of Enalapril Versus Propranolol or Atenolol for Prevention of Aortic Dilation in Patients With the Marfan Syndrome
2005· article· en· The American Journal of Cardiology· Biochemistry, Genetics and Molecular Biology
affno abstract
169
citations
Outcomes of Aortic Valve-Sparing Operations in Marfan Syndrome
2015· article· en· Journal of the American College of Cardiology· Medicine
affno abstract
130
citations
Loss-of-function mutations in the X-linked biglycan gene cause a severe syndromic form of thoracic aortic aneurysms and dissections
2016· article· en· Genetics in Medicine· Biochemistry, Genetics and Molecular Biology
aff
127
citations
Long-term results of aortic root repair using the reimplantation technique
2012· article· en· Journal of Thoracic and Cardiovascular Surgery· Medicine
affno abstract
123
citations
Early and 1-year outcomes of aortic root surgery in patients with Marfan syndrome: A prospective, multicenter, comparative study
2014· article· en· Journal of Thoracic and Cardiovascular Surgery· Medicine
fundno affno abstract
122
citations
Long-term results of aortic valve–sparing operations in patients with Marfan syndrome
2009· article· en· Journal of Thoracic and Cardiovascular Surgery· Medicine
affno abstract
121
citations
Endothelial dysfunction and compromised eNOS/Akt signaling in the thoracic aorta during the progression of Marfan syndrome
2007· article· en· British Journal of Pharmacology· Biochemistry, Genetics and Molecular Biology
afffund
118
citations
Root Replacement Surgery Versus More Conservative Management During Type A Acute Aortic Dissection Repair
2014· article· en· The Annals of Thoracic Surgery· Medicine
affno abstract
118
citations
Angiotensin receptor blockers and β blockers in Marfan syndrome: an individual patient data meta-analysis of randomised trials
2022· review· en· The Lancet· Biochemistry, Genetics and Molecular Biology
aff
115
citations