Smad7 Binds to Smurf2 to Form an E3 Ubiquitin Ligase that Targets the TGFβ Receptor for Degradation
2000· article· en· Molecular Cell· Biochemistry, Genetics and Molecular Biology
affno abstract
1,332
citations
Works
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Syk- and CARD9-dependent coupling of innate immunity to the induction of T helper cells that produce interleukin 17
2007· article· en· Nature Immunology· Medicine
affno abstract
1,166
citations
cIAP1 and cIAP2 Facilitate Cancer Cell Survival by Functioning as E3 Ligases that Promote RIP1 Ubiquitination
2008· article· en· Molecular Cell· Biochemistry, Genetics and Molecular Biology
affno abstract
1,087
citations
Integral role of IRF-5 in the gene induction programme activated by Toll-like receptors
2005· article· en· Nature· Immunology and Microbiology
affno abstract
1,009
citations
Inflammasome activation and regulation: toward a better understanding of complex mechanisms
2020· review· en· Cell Discovery· Biochemistry, Genetics and Molecular Biology
fundno aff
1,001
citations
Clathrin- and non-clathrin-mediated endocytic regulation of cell signalling
2005· review· en· Nature Reviews Molecular Cell Biology· Biochemistry, Genetics and Molecular Biology
afffundno abstract
861
citations
Neurotrophin signaling through the p75 neurotrophin receptor
2002· review· en· Progress in Neurobiology· Neuroscience
affno abstract
709
citations
Negative regulation of lymphocyte activation and autoimmunity by the molecular adaptor Cbl-b
2000· article· en· Nature· Immunology and Microbiology
affno abstract
668
citations
Molecular architecture and assembly of the DDB1–CUL4A ubiquitin ligase machinery
2006· article· en· Nature· Biochemistry, Genetics and Molecular Biology
affno abstract
667
citations
T cell receptor ligation induces the formation of dynamically regulated signaling assemblies
2002· article· en· The Journal of Cell Biology· Immunology and Microbiology
aff
620
citations
Lipopolysaccharide signaling in endothelial cells
2005· review· en· Laboratory Investigation· Immunology and Microbiology
affno abstract
613
citations
The adaptor Act1 is required for interleukin 17–dependent signaling associated with autoimmune and inflammatory disease
2007· article· en· Nature Immunology· Immunology and Microbiology
affno abstract
604
citations
Integrin-linked kinase: a cancer therapeutic target unique among its ILK
2005· review· en· Nature reviews. Cancer· Medicine
afffundno abstract
597
citations
The Adaptor Protein p62/SQSTM1 Targets Invading Bacteria to the Autophagy Pathway
2009· article· en· The Journal of Immunology· Medicine
aff
568
citations
The Hippo Pathway Regulates Wnt/β-Catenin Signaling
2010· article· en· Developmental Cell· Biochemistry, Genetics and Molecular Biology
afffundno abstract
566
citations
Both cIAP1 and cIAP2 regulate TNFα-mediated NF-κB activation
2008· article· en· Proceedings of the National Academy of Sciences· Biochemistry, Genetics and Molecular Biology
afffund
528
citations
Bcl10 activates the NF-κB pathway through ubiquitination of NEMO
2003· article· en· Nature· Biochemistry, Genetics and Molecular Biology
affno abstract
526
citations
Nck adaptor proteins link nephrin to the actin cytoskeleton of kidney podocytes
2006· article· en· Nature· Medicine
affno abstract
480
citations
NOD-like receptors and inflammasomes: A review of their canonical and non-canonical signaling pathways
2019· review· en· Archives of Biochemistry and Biophysics· Biochemistry, Genetics and Molecular Biology
afffundno abstract
476
citations
A hitchhiker's guide to the cullin ubiquitin ligases: SCF and its kin
2004· review· en· Biochimica et Biophysica Acta (BBA) - Molecular Cell Research· Biochemistry, Genetics and Molecular Biology
affno abstract
459
citations
Clathrin Adaptor AP2 and NSF Interact with Overlapping Sites of GluR2 and Play Distinct Roles in AMPA Receptor Trafficking and Hippocampal LTD
2002· article· en· Neuron· Biochemistry, Genetics and Molecular Biology
afffundno abstract
440
citations
The BTB protein MEL-26 is a substrate-specific adaptor of the CUL-3 ubiquitin-ligase
2003· article· en· Nature· Biochemistry, Genetics and Molecular Biology
affno abstract
419
citations
A multiprotein supercomplex controlling oncogenic signalling in lymphoma
2018· article· en· Nature· Medicine
affno abstract
403
citations
Toll-like receptor 3-mediated activation of NF-κB and IRF3 diverges at Toll-IL-1 receptor domain-containing adapter inducing IFN-β
2004· article· en· Proceedings of the National Academy of Sciences· Immunology and Microbiology
aff
384
citations
Enteropathogenic E. coli Tir binds Nck to initiate actin pedestal formation in host cells
2001· article· en· Nature Cell Biology· Biochemistry, Genetics and Molecular Biology
affno abstract
361
citations