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Neurotrophin signaling through the p75 neurotrophin receptor

2002· review· en· 709 citations· W1967336797 on OpenAlex· 10.1016/s0301-0082(02)00016-3

Why is this work in the frame?

A frame that forgets how it found something cannot be audited. These are the routes that admitted this work.

Canadian affiliationAn author listed a Canadian institution. This is the only route the usual frame has.

Classifier prediction

metacan-v1-d91a1de5be90

Predictions imitate two machine teachers. Scores are not calibrated prevalence probabilities.

Classifier candidate
Bench or experimentalNot applicable
Classifier consensus
N/A
Teacher imitation scores

Codex

Other design0.065
Bench or experimental0.056
Theoretical or conceptual0.013
Metaresearch0.002
Case report0.001
Systematic review0.001
Research integrity0.001
Scholarly communication0.000
Simulation or modelling0.000
Science and technology studies0.000
Meta-analysis0.000
Meta-epidemiology (broad)0.000
Observational0.000
Bibliometrics0.000
Open science0.000
Non-randomized trial0.000
Meta-epidemiology (narrow)0.000
Qualitative0.000
Not applicable0.000
Randomized trial0.000

Gemma

Not applicable0.738
Bench or experimental0.108
Systematic review0.001
Theoretical or conceptual0.001
Science and technology studies0.001
Meta-epidemiology (broad)0.000
Case report0.000
Metaresearch0.000
Research integrity0.000
Open science0.000
Bibliometrics0.000
Meta-analysis0.000
Simulation or modelling0.000
Non-randomized trial0.000
Meta-epidemiology (narrow)0.000
Scholarly communication0.000
Randomized trial0.000
Observational0.000
Qualitative0.000

Machine scores (provisional)

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Opus teacher head0.127
GPT teacher head0.362
Teacher spread
0.236 how far apart the two teachers sit on this one work
Validation status
score_only:v0-immature-baseline verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Abstract

The neurotrophins are growth factors that play critical roles in the development, maintenance, survival, and death of the nervous system. The signal transducing systems that mediate the diverse biological functions of the neurotrophins are initiated by their interactions with two categories of cell surface receptors, the Trk family of tyrosine kinases and the p75 neurotrophin receptor (p75NTR). While the Trk receptors are responsible for most of the survival and growth properties of the neurotro…

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