Neurotrophin signal transduction in the nervous system
2000· review· en· Current Opinion in Neurobiology· Neuroscience
affno abstract
1,945
citations
Works
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206 workspage 1 of 9
Neurotrophin signaling through the p75 neurotrophin receptor
2002· review· en· Progress in Neurobiology· Neuroscience
affno abstract
709
citations
BDNF Promotes the Regenerative Sprouting, But Not Survival, of Injured Serotonergic Axons in the Adult Rat Brain
2000· article· en· Journal of Neuroscience· Neuroscience
aff
344
citations
Neurotrophin signalling pathways regulating neuronal apoptosis
2001· review· en· Cellular and Molecular Life Sciences· Neuroscience
affno abstract
314
citations
Cell Surface Trk Receptors Mediate NGF-Induced Survival While Internalized Receptors Regulate NGF-Induced Differentiation
2000· article· en· Journal of Neuroscience· Neuroscience
afffund
309
citations
Interaction of Survival and Death Signaling in Basal Forebrain Neurons: Roles of Neurotrophins and Proneurotrophins
2006· article· en· Journal of Neuroscience· Neuroscience
aff
263
citations
The Cytoplasmic and Transmembrane Domains of the p75 and Trk A Receptors Regulate High Affinity Binding to Nerve Growth Factor
2001· article· en· Journal of Biological Chemistry· Neuroscience
aff
229
citations
Trk signaling regulates neural precursor cell proliferation and differentiation during cortical development
2007· article· en· Development· Neuroscience
aff
219
citations
Improving peripheral nerve regeneration: From molecular mechanisms to potential therapeutic targets
2014· review· en· Experimental Neurology· Neuroscience
afffundno abstract
195
citations
Efficacy and safety of larotrectinib in TRK fusion-positive primary central nervous system tumors
2021· article· en· Neuro-Oncology· Medicine
aff
170
citations
RTK and TGF-β signaling pathways genes in the sea urchin genome
2006· article· en· Developmental Biology· Biochemistry, Genetics and Molecular Biology
affno abstract
157
citations
157
citations
Efficacy and safety of larotrectinib in patients with TRK fusion-positive thyroid carcinoma
2022· article· en· European Journal of Endocrinology· Medicine
aff
145
citations
JSCO—ESMO—ASCO—JSMO—TOS: international expert consensus recommendations for tumour-agnostic treatments in patients with solid tumours with microsatellite instability or NTRK fusions
2020· article· en· Annals of Oncology· Medicine
fundno affno abstract
139
citations
Efficacy and safety of larotrectinib in patients with TRK fusion-positive thyroid carcinoma
2022· article· en· The Medicine Forum· Medicine
aff
125
citations
Suppression of anoikis by the neurotrophic receptor TrkB in human ovarian cancer
2008· article· en· Cancer Science· Medicine
aff
120
citations
Changes in retinal expression of neurotrophins and neurotrophin receptors induced by ocular hypertension
2004· article· en· Journal of Neurobiology· Medicine
aff
120
citations
Development of pharmacological agents for targeting neurotrophins and their receptors
2000· review· en· Trends in Pharmacological Sciences· Neuroscience
affno abstract
119
citations
The neurotrophic effects of PACAP in PC12 cells: control by multiple transduction pathways
2006· review· en· Journal of Neurochemistry· Neuroscience
aff
116
citations
Receptor binding, internalization, and retrograde transport of neurotrophic factors
2001· review· en· Cellular and Molecular Life Sciences· Neuroscience
affno abstract
114
citations
TrkA mediates developmental sympathetic neuron survival in vivo by silencing an ongoing p75NTR-mediated death signal
2001· article· en· The Journal of Cell Biology· Neuroscience
aff
113
citations
A kinase-deficient TrkC receptor isoform activates Arf6–Rac1 signaling through the scaffold protein tamalin
2006· article· en· The Journal of Cell Biology· Neuroscience
aff
111
citations
K252a and CEP1347 Are Neuroprotective Compounds That Inhibit Mixed-lineage Kinase-3 and Induce Activation of Akt and ERK
2002· article· en· Journal of Biological Chemistry· Biochemistry, Genetics and Molecular Biology
aff
100
citations
p75 neurotrophin receptor reduces ligand‐induced Trk receptor ubiquitination and delays Trk receptor internalization and degradation
2005· article· en· EMBO Reports· Neuroscience
afffundno abstract
98
citations
p75 Co-receptors Regulate Ligand-dependent and Ligand-independent Trk Receptor Activation, in Part by Altering Trk Docking Subdomains
2001· article· en· Journal of Biological Chemistry· Neuroscience
aff
97
citations