Notice bibliographique
Résumé
Abiomedical sciences professor was awarded the first Canada Research Chair (CRC) at the Ontario Veterinary College in November. Dr. Jonathon LaMarre will hold a junior chair in Comparative Biomedical Sciences for the next 5 years. The Canada Research Chairs Program, launched by the federal government in 2000, is designed to help Canadian universities become world-class research centers by providing them with new funds to recruit and retain outstanding faculty. Dr. LaMarre is an internationally recognized scientist whose research focuses on the regulation of gene expression in multiple species and tissues. He is currently studying the regulation of genes responsible for cell differentiation, growth, and angiogenesis, with the hope that this work will eventually translate into improved diagnosis and treatment of disease. “The idea is to look at very basic concepts about genes and how the genes are regulated, and ultimately to apply these concepts to animal and human disease,” he says. “Understanding the processes behind the regulation of gene expression is particularly important in the context of human and animal health where disturbances in normal control mechanisms contribute to the pathogenesis of many diseases.” Dr. LaMarre's research is comparative in every sense; he examines gene expression in multiple species models, including human, rat, murine, and bovine, and in different types of tissue within single species. He also compares gene regulation in normal and malignant cells. He is currently studying liver tissue and the regulation of hepatic lipoprotein receptor-related protein (LRP) synthesis. Lipoprotein receptor-related protein is a receptor implicated in atherosclerosis, tumor growth, and several other conditions, including Alzheimer's and cirrhosis. Dr. LaMarre hopes the Canada Research Chair will help him to recruit more talented young scientists to his laboratory. He currently supervises 2 PhD students, a postdoctoral fellow, and a technician. “One of the reasons I'm excited about this (Canada Research Chair) is it gives me the opportunity to train people who will become the next generation of investigators,” he says. Dr. LaMarre earned his DVM and PhD degrees at Guelph and has been a faculty member at OVC since 1993. His laboratory has received operating grants from the Canadian Institute of Health Research, formerly known as the Medical Research Council (MRC), since 1994. He also received funding from the MRC for both his PhD in Pathobiology and for the postdoctoral position he held at the University of Virginia Medical School. (by Natasha Marko, Public Relations Officer, Ontario Veterinary College, Guelph, Ontario)
Récupéré en direct depuis OpenAlex et désinversé. Les résumés ne sont pas conservés dans cette base de données : les index inversés représentent 8,6 Go des 9,3 Go de texte de la base, et le serveur dispose de 13 Go libres.
Comment cette classification a été obtenuedéplier
Prédiction machine sur la base complète
Imitation des enseignantsNi prévalence calibrée, ni vérité terrain. Validation humaine à venir. Le volet Gemma est une étiquette directe du modèle pour chaque travail de la base, lue sur la notice réduite au titre. Le volet Codex est un classifieur appris des 10 348 étiquettes directes de Codex et calibré sur les taux pondérés de l'échantillon; les champs sans appui suffisant ne portent aucun appel Codex. Le mode candidate est l'union des deux volets; le consensus est leur intersection. Ces sorties portent le statut machine_predicted_unvalidated et ne sont pas des étiquettes humaines.
Scores du classifieur distillé par catégorie (deux têtes)
| Catégorie | Codex | Gemma |
|---|---|---|
| Métarecherche | 0,003 | 0,005 |
| Méta-épidémiologie (sens strict) | 0,001 | 0,001 |
| Méta-épidémiologie (sens large) | 0,001 | 0,001 |
| Bibliométrie | 0,003 | 0,002 |
| Études des sciences et des technologies | 0,004 | 0,002 |
| Communication savante | 0,006 | 0,002 |
| Science ouverte | 0,001 | 0,002 |
| Intégrité de la recherche | 0,005 | 0,005 |
| Charge utile insuffisante (le modèle a refusé de juger) | 0,160 | 0,049 |
Scores machine (provisoires)
Les deux têtes enseignantes du modèle étudiant, lues sur ce travail. Un score ordonne la base pour la relecture; il n'affirme jamais une catégorie, et le statut de validation accompagne chaque rangée tel quel.
Scores de référence d'un modèle non mature (critères de maturité non atteints, 7 itérations). Un score ordonne; il n'affirme jamais une catégorie.
score_only:v0-immature-baseline · tel quel depuis la passe de notation : score_only signifie que le nombre peut ordonner les travaux, et qu'aucune étiquette de catégorie n'en découleClassification
machine, non validéePrédiction automatique; un appel candidat d’une seule source (Gemma direct ou Codex distillé), pas un consensus.
Le détail, modèle par modèle et score par score, se trouve en fin de page sous « Comment cette classification a été obtenue ».