P1-S2.69 Prevalence of HPV infections in Metis and First Nations living in Manitoba, Canada
Notice bibliographique
Résumé
Background Information on human papillomavirus (HPV) prevalence among Aboriginal populations (First Nations, Métis, Inuit) in Canada remains scarce but is needed for informed public health programming. This need is reinforced by the rapidly changing rates of cervical cancer screening in these populations and the introduction of prophylactic vaccines. Method In 2008, 52 clinics across the province of Manitoba, Canada participated in a Pap Week initiative during which left over tissues from conventional Pap tests were used for HPV typing using the Luminex method (developed by the National Microbiology Laboratory). A risk-behaviour survey was also administered to consenting women. Chi-square was used to compare frequencies and logistic regression was used to model the data. The most significant factors were included in the multivariate logistic model. Results Of 592 women recruited, 113 self-reported being Meti or First Nations (M/FN); 70 did not report their ethnic background and were excluded from the analysis. M/FN participants were younger than the non-M/FN participants (mean age: 39 vs 45, p<0.0001). HPV infection prevalence was 2.3 times higher in M/FN than in other participants (32.7% vs 14.2%, p<0.0001). This increase was mainly due to the higher prevalence of HPV 32, 35, 51, 58, and 62. The prevalence of HPV 16 and 18 in the M/FN population was comparable to that of the non-M/FN (p=0.64), although HPV 18 slightly higher in M/FN (5.6% vs 3.8%). Compared to their non-Aboriginal counterparts, M/FN women participating in the study were more often smokers (p<0.0001), had a higher number of sexual partners in the last year (p=0.0004), and were more often in an unstable relationship (p=0.03). The strongest predictors for HPV infection in the study population were the number of sexual partners over the last year (OR 5.71; 95% CI 3.08 to 10.58) and having reported a M/FN identity (OR 2.17; 95% CI 1.28 to 3.69). Conclusion Certain types of HPV may be more prevalent in M/FN than in the non-Aboriginal population. Although it is clear that the HPV vaccine has the potential to lower the prevalence of HPV 6, 11, 16, and 18 infections and related diseases in the M/FN population living in Manitoba, its impact could be mitigated by the relatively high prevalence of other HPV types.
Récupéré en direct depuis OpenAlex et désinversé. Les résumés ne sont pas conservés dans cette base de données : les index inversés représentent 8,6 Go des 9,3 Go de texte de la base, et le serveur dispose de 13 Go libres.
Comment cette classification a été obtenuedéplier
Prédiction distillée sur la base complète
Imitation des enseignantsNi prévalence calibrée, ni vérité terrain. Validation humaine à venir. Apprise à partir de 10 348 étiquettes directes de Codex et de 10 348 étiquettes directes de Gemma. Le mode candidate est l'union des têtes enseignantes seuillées; le consensus est leur intersection. Ces sorties portent le statut machine_predicted_unvalidated et ne sont ni des étiquettes humaines ni des étiquettes directes de modèles de pointe.
Scores Codex et Gemma par catégorie
| Catégorie | Codex | Gemma |
|---|---|---|
| Métarecherche | 0,000 | 0,000 |
| Méta-épidémiologie (sens strict) | 0,000 | 0,000 |
| Méta-épidémiologie (sens large) | 0,000 | 0,000 |
| Bibliométrie | 0,001 | 0,001 |
| Études des sciences et des technologies | 0,000 | 0,000 |
| Communication savante | 0,000 | 0,000 |
| Science ouverte | 0,000 | 0,000 |
| Intégrité de la recherche | 0,000 | 0,000 |
| Charge utile insuffisante (le modèle a refusé de juger) | 0,004 | 0,000 |
Scores machine (provisoires)
Les deux têtes enseignantes du modèle étudiant, lues sur ce travail. Un score ordonne la base pour la relecture; il n'affirme jamais une catégorie, et le statut de validation accompagne chaque rangée tel quel.
Scores de référence d'un modèle non mature (critères de maturité non atteints, 7 itérations). Un score ordonne; il n'affirme jamais une catégorie.
score_only:v0-immature-baseline · tel quel depuis la passe de notation : score_only signifie que le nombre peut ordonner les travaux, et qu'aucune étiquette de catégorie n'en découleClassification
machine, non validéePrédiction automatique; un appel candidat d’une seule tête enseignante, pas un consensus.
Le détail, modèle par modèle et score par score, se trouve en fin de page sous « Comment cette classification a été obtenue ».