Incidence of postmenopausal symptoms and current mamagement: a survey of 260 breast cancer patients.
Notice bibliographique
Résumé
Abstract Abstract #3117 Background: The advent of newer and more efficacious adjuvant treatments has allowed women to live longer without cancer recurrence. However these treatments often prematurely induce menopause, worsen menopausal symptoms and may have long-term effects on postmenopausal health. The objectives of this study were to examine the incidence of post-menopausal symptoms and how such symptoms are currently being managed outside of a clinical trial setting, in order to better facilitate patient care. Methods: A self-administered questionnaire was completed by 260 postmenopausal breast cancer patients assessing treatment-induced side effects, how patients were monitored and patient follow-up. Descriptive statistics were used to describe results. Parametric and non-parametric inferential statistics were used in an exploratory analysis to compare post-menopausal symptoms between patient subgroups. Results: Of the 260 patients, 48% percent received endocrine therapy, 17.7% received chemotherapy and 26.2% were not on any therapy at the time of this study. The most common reported symptom was hot flashes (49.2%). Other common reported symptoms were difficulty sleeping (44.6%), weight gain (35.9%), memory problems (33.1%), and vaginal dryness (32.7%). Statistically significant correlations were identified between the use of aromatase inhibitors and the development of hypercholesterolemia and osteopenia. In contrast, the use of tamoxifen was significantly associated with the occurrence of vaginal symptoms such as dryness, itching and bleeding. Majority of patients were also monitored by their family physician with cholesterol monitoring (84%) and bone densitometry (68.1%) either yearly or every two years. Though most patients (83.5%) felt that their medical oncologist should monitor their breast cancer, they preferred to discuss their endocrine symptoms with their family physician (57.9%). Conclusions: The incidence and association of symptoms reported were consistent with the current literature. The management of long-term consequences of breast cancer therapies is going to remain a major part of our role as medical oncologists. However, involvement of family physicians in management of symptoms seems to be preferred by many patients. Citation Information: Cancer Res 2009;69(2 Suppl):Abstract nr 3117.
Récupéré en direct depuis OpenAlex et désinversé. Les résumés ne sont pas conservés dans cette base de données : les index inversés représentent 8,6 Go des 9,3 Go de texte de la base, et le serveur dispose de 13 Go libres.
Comment cette classification a été obtenuedéplier
Prédiction machine sur la base complète
Imitation des enseignantsNi prévalence calibrée, ni vérité terrain. Validation humaine à venir. Le volet Gemma est une étiquette directe du modèle pour chaque travail de la base, lue sur la notice réduite au titre. Le volet Codex est un classifieur appris des 10 348 étiquettes directes de Codex et calibré sur les taux pondérés de l'échantillon; les champs sans appui suffisant ne portent aucun appel Codex. Le mode candidate est l'union des deux volets; le consensus est leur intersection. Ces sorties portent le statut machine_predicted_unvalidated et ne sont pas des étiquettes humaines.
Scores du classifieur distillé par catégorie (deux têtes)
| Catégorie | Codex | Gemma |
|---|---|---|
| Métarecherche | 0,001 | 0,002 |
| Méta-épidémiologie (sens strict) | 0,000 | 0,000 |
| Méta-épidémiologie (sens large) | 0,000 | 0,000 |
| Bibliométrie | 0,001 | 0,001 |
| Études des sciences et des technologies | 0,000 | 0,000 |
| Communication savante | 0,000 | 0,000 |
| Science ouverte | 0,000 | 0,000 |
| Intégrité de la recherche | 0,000 | 0,000 |
| Charge utile insuffisante (le modèle a refusé de juger) | 0,001 | 0,000 |
Scores machine (provisoires)
Les deux têtes enseignantes du modèle étudiant, lues sur ce travail. Un score ordonne la base pour la relecture; il n'affirme jamais une catégorie, et le statut de validation accompagne chaque rangée tel quel.
Scores de référence d'un modèle non mature (critères de maturité non atteints, 7 itérations). Un score ordonne; il n'affirme jamais une catégorie.
score_only:v0-immature-baseline · tel quel depuis la passe de notation : score_only signifie que le nombre peut ordonner les travaux, et qu'aucune étiquette de catégorie n'en découleClassification
machine, non validéePrédiction automatique; un appel candidat d’une seule source (Gemma direct ou Codex distillé), pas un consensus.
Le détail, modèle par modèle et score par score, se trouve en fin de page sous « Comment cette classification a été obtenue ».