Genome-Wide Analysis of the World's Sheep Breeds Reveals High Levels of Historic Mixture and Strong Recent Selection
Pourquoi ce travail est-il dans la base ?
Une base qui oublie comment elle a trouvé un travail ne peut pas être vérifiée. Voici les voies qui ont admis celui-ci.
Aucune affiliation canadienne. Une base fondée sur la seule affiliation (le devis habituel) n'aurait jamais vu ce travail. C'est l'un des travaux qui justifient l'inversion de la base.
Résumé
Through their domestication and subsequent selection, sheep have been adapted to thrive in a diverse range of environments. To characterise the genetic consequence of both domestication and selection, we genotyped 49,034 SNP in 2,819 animals from a diverse collection of 74 sheep breeds. We find the majority of sheep populations contain high SNP diversity and have retained an effective population size much higher than most cattle or dog breeds, suggesting domestication occurred from a broad genetic base. Extensive haplotype sharing and generally low divergence time between breeds reveal frequent genetic exchange has occurred during the development of modern breeds. A scan of the genome for selection signals revealed 31 regions containing genes for coat pigmentation, skeletal morphology, body size, growth, and reproduction. We demonstrate the strongest selection signal has occurred in response to breeding for the absence of horns. The high density map of genetic variability provides an in-depth view of the genetic history for this important livestock species.
Récupéré en direct depuis OpenAlex et désinversé. Les résumés ne sont pas conservés dans cette base de données : les index inversés représentent 8,6 Go des 9,3 Go de texte de la base, et le serveur dispose de 13 Go libres.
La notice
- Revue
- PLoS Biology
- Thématique
- Genetic and phenotypic traits in livestock
- Domaine
- Biochemistry, Genetics and Molecular Biology
- Établissements canadiens
- —
- Organismes subventionnaires
- National Chemical LaboratoryAristotle University of ThessalonikiHáskóli ÍslandsUniversity College DublinUniversity of CyprusUniversity of AlbertaUniversidad de LeónAdnan Menderes ÜniversitesiUniversity of PeradeniyaInstitut National de la Recherche AgronomiqueUniversity of New EnglandCommonwealth Scientific and Industrial Research OrganisationInstitute of GeneticsCyprus University of TechnologyUniversität HohenheimChinese Academy of Agricultural SciencesInternational Atomic Energy AgencyLandbúnaðarháskóli ÍslandsMeat and Livestock AustraliaU.S. Department of Agriculture
- Mots-clés
- BiologyDomesticationSelection (genetic algorithm)Genetic diversityEvolutionary biologyCoatGenetic variationPopulationLivestockGeneticsHaplotypeGeneGenotypeEcology
- Résumé présent dans OpenAlex
- oui