Redundant Data in the Meta-analysis on <i>Helicobacter pylori</i> Eradication
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Résumé
Letters6 October 2009Redundant Data in the Meta-analysis on Helicobacter pylori EradicationAlexander C. Ford, MBChB, MD and Paul Moayyedi, MBChB, PhDAlexander C. Ford, MBChB, MDFrom St. James's University Hospital, Leeds LS9 7TF, United Kingdom; and McMaster University Health Sciences Centre, Hamilton, Ontario L8N 3Z5, Canada. and Paul Moayyedi, MBChB, PhDFrom St. James's University Hospital, Leeds LS9 7TF, United Kingdom; and McMaster University Health Sciences Centre, Hamilton, Ontario L8N 3Z5, Canada.Author, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-151-7-200910060-00014 SectionsAboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail TO THE EDITOR:We read with interest the recent meta-analysis by Fuccio and colleagues (1). There is an ongoing Cochrane review on this subject; its protocol is published (2), and its results have been reported in abstract form (3). Fuccio and colleagues report that eradication therapy for Helicobacter pylori reduces the subsequent incidence of gastric cancer. However, we have serious doubts about the accuracy of their analysis. In the Methods section of their article, Fuccio and colleagues state that when they found multiple articles for a single study, they used the latest publication from each eligible study. However, the meta-analysis ...References1. Fuccio L, Zagari RM, Eusebi LH, Laterza L, Cennamo V, Ceroni L, et al. Meta-analysis: can Helicobacter pylori eradication treatment reduce the risk for gastric cancer? Ann Intern Med. 2009;151:121-8. [PMID: 19620164] LinkGoogle Scholar2. Moayyedi P, Hunt R, Forman D. Helicobacter pylori eradication for the prevention of gastric neoplasia. Cochrane Database Syst Rev. 2006;1:CD005583. Google Scholar3. Moayyedi P, Hunt RH, Ford AC, Talley NJ, Forman D. Helicobacter pylori eradication reduces the incidence of gastric cancer: results of a systematic review of randomized controlled trials [Abstract]. Gastroenterology. 2008;134:A631-2. CrossrefGoogle Scholar4. Leung WK, Lin SR, Ching JY, To KF, Ng EK, Chan FK, et al. Factors predicting progression of gastric intestinal metaplasia: results of a randomised trial on Helicobacter pylori eradication. Gut. 2004;53:1244-9. [PMID: 15306578] CrossrefMedlineGoogle Scholar5. Zhou L. Ten-year follow-up study on the incidence of gastric cancer and the pathological changes of gastric mucosa after H. pylori eradication in China [Abstract]. Gastroenterology. 2008;134:A233. CrossrefGoogle Scholar Author, Article, and Disclosure InformationAuthors: Alexander C. Ford, MBChB, MD; Paul Moayyedi, MBChB, PhDAffiliations: From St. James's University Hospital, Leeds LS9 7TF, United Kingdom; and McMaster University Health Sciences Centre, Hamilton, Ontario L8N 3Z5, Canada.Disclosures: None disclosed. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetailsSee AlsoMeta-analysis: Can Helicobacter pylori Eradication Treatment Reduce the Risk for Gastric Cancer? Lorenzo Fuccio , Rocco Maurizio Zagari , Leonardo Henry Eusebi , Liboria Laterza , Vincenzo Cennamo , Liza Ceroni , Diego Grilli , and Franco Bazzoli Redundant Data in the Meta-analysis on Helicobacter pylori Eradication Lorenzo Fuccio , Leonardo Henry Eusebi , and Franco Bazzoli Metrics Cited byHelicobacter pylori eradication for the prevention of gastric neoplasiaEffectiveness of Helicobacter pylori eradication in the prevention of primary gastric cancer in healthy asymptomatic people: A systematic review and meta-analysis comparing risk ratio with risk differenceEffect of Helicobacter pylori Eradication on Gastric Cancer Prevention in Korea: A Randomized Controlled Clinical TrialSerum pepsinogen levels can quantify the risk of development of metachronous gastric cancer after endoscopic resectionGastric CancerHelicobacter pylori eradication cannot reduce the risk of gastric cancer in patients with intestinal metaplasia and dysplasia: evidence from a meta-analysisHelicobacter pylori eradication for the prevention of gastric neoplasiaHow to Read a Systematic Review and Meta-AnalysisCancer Prevention, Screening, and Early DetectionManagement of Helicobacter pylori infection in Latin America: A Delphi technique-based consensusStatins are associated with reduced risk of gastric cancer: a systematic review and meta-analysisHow Long Will It Take to Reduce Gastric Cancer Incidence by Eradicating Helicobacter Pylori Infection?Recent Development of Gastric Cancer PreventionLong-term effect of Helicobacter pylori eradication on the development of metachronous gastric cancer after endoscopic resection of early gastric cancerChemoprevention for gastric cancer 6 October 2009Volume 151, Issue 7Page: 513KeywordsConflicts of interestGastric cancerHelicobacter pyloriRelative riskStatistical dataSystematic reviews ePublished: 6 October 2009 Issue Published: 6 October 2009 Copyright & PermissionsCopyright © 2009 by American College of Physicians. 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Récupéré en direct depuis OpenAlex et désinversé. Les résumés ne sont pas conservés dans cette base de données : les index inversés représentent 8,6 Go des 9,3 Go de texte de la base, et le serveur dispose de 13 Go libres.
Comment cette classification a été obtenuedéplier
Prédiction machine sur la base complète
Imitation des enseignantsNi prévalence calibrée, ni vérité terrain. Validation humaine à venir. Le volet Gemma est une étiquette directe du modèle pour chaque travail de la base, lue sur la notice réduite au titre. Le volet Codex est un classifieur appris des 10 348 étiquettes directes de Codex et calibré sur les taux pondérés de l'échantillon; les champs sans appui suffisant ne portent aucun appel Codex. Le mode candidate est l'union des deux volets; le consensus est leur intersection. Ces sorties portent le statut machine_predicted_unvalidated et ne sont pas des étiquettes humaines.
Scores du classifieur distillé par catégorie (deux têtes)
| Catégorie | Codex | Gemma |
|---|---|---|
| Métarecherche | 0,308 | 0,635 |
| Méta-épidémiologie (sens strict) | 0,003 | 0,003 |
| Méta-épidémiologie (sens large) | 0,013 | 0,019 |
| Bibliométrie | 0,008 | 0,013 |
| Études des sciences et des technologies | 0,002 | 0,003 |
| Communication savante | 0,008 | 0,008 |
| Science ouverte | 0,006 | 0,005 |
| Intégrité de la recherche | 0,008 | 0,009 |
| Charge utile insuffisante (le modèle a refusé de juger) | 0,007 | 0,001 |
Scores machine (provisoires)
Les deux têtes enseignantes du modèle étudiant, lues sur ce travail. Un score ordonne la base pour la relecture; il n'affirme jamais une catégorie, et le statut de validation accompagne chaque rangée tel quel.
Scores de référence d'un modèle non mature (critères de maturité non atteints, 7 itérations). Un score ordonne; il n'affirme jamais une catégorie.
score_only:v0-immature-baseline · tel quel depuis la passe de notation : score_only signifie que le nombre peut ordonner les travaux, et qu'aucune étiquette de catégorie n'en découleClassification
machine, non validéePrédiction automatique; l’étiquette directe de Gemma et le classifieur distillé Codex s’accordent sur ce qui est montré ici.
Le détail, modèle par modèle et score par score, se trouve en fin de page sous « Comment cette classification a été obtenue ».