MétaCan
Menu
Retour à la cohorte
Enregistrement W2081739117 · doi:10.1097/01.mat.0000088801.66021.f8

A Multibillion Dollar Industry, But Not for Poor Countries

2003· article· en· W2081739117 sur OpenAlexaboutno aff
Willem J. Kolff

Notice bibliographique

RevueASAIO Journal · 2003
Typearticle
Langueen
DomaineMedicine
ThématiqueOrgan Donation and Transplantation
Établissements canadiensnon disponible
Organismes subventionnairesnon disponible
Mots-clésLiberian dollarGermanNazismArtificial kidneyEconomic historyFactory (object-oriented programming)SalaryMedicineArt historyPolitical scienceEngineeringHistoryLawBusinessFinanceInternal medicine

Résumé

récupéré en direct d'OpenAlex

This morning, the 15th of July, 2003, I woke up about 6 o’clock, and I suddenly realized that on the 17th of March, 1943, that is 60 years ago, the first patient was treated with the rotating drum artificial kidney in Kampen, the Netherlands. It was the beginning of artificial organs, and I could not remember that I have heard anywhere or seen anywhere a statement that says that this was also the beginning of a multibillion dollar industry worldwide. I started to try to make an artificial kidney in 1939 in Groningen, the Netherlands, but I had very little money. When early during the war in 1941 I was appointed the first internist at the hospital in Kampen (at a salary of $3,000 per year, or a total income of about 10,000 guilders per year), I decided that financial need would no longer keep me from making an artificial kidney. I went to the Kampen enamel factory and spoke with Mr. Henk Berk, who made the rotating drum artificial kidney for me. Actually, I never paid for it because they were only allowed to work for the German Wehrmacht. When I had seen the obvious effect of dialysis in patients, I decided to make more artificial kidneys so that I would be able to send them to other countries right after the war. The Wagenmaker (which I believe is translated as “wheelwright”) in the Granfschap in Kampen made the wooden drums. The first series of four artificial kidneys consisted of a large wooden drum that rotated through a 100 liter tank of dialyzing fluid, which is basically saline. I did not have to pay for the 100 liter enamel tanks; they were donated by Berk’s enamel factory. The metal frames were ordered somewhere else. To pay for the motors that were standing on the floor to rotate the wooden drums, we had to fill out numerous forms, as the motors were made in Germany. The artificial kidneys were hidden in several places in the city of Kampen so that they would not be destroyed if bombs fell, but no bombs fell. Three artificial kidneys were sent abroad after the war: one to Hammersmith Hospital in London, one to Mount Sinai Hospital in New York, and one to the Royal Victoria Hospital in Montreal. I did not realize at the time that when wartime industry was changing to peacetime industry, there would be no time for such a thing as an artificial kidney. The first patient I treated with the artificial kidney was Miss Schriver, a 28 year old housemaid, daughter of a small farmer. When after 12 dialyses she died, her father came up to pay the bill, and I charged him 6 guilders per dialysis, or a total of 60 guilders. He had seen the enormous care and effort we had spent on his daughter. Once our transaction was completed, he stood up and thanked me, and I immediately went down to pay the bill. In 1950 I came to the Cleveland Clinic, and payment for dialysis became an immediate problem. Dialysis Does Not Need to Be Expensive We took a Maytag washing machine and made a small dialysis machine for which a patient could wind his own coil kidney, provided cellophane and dialyzing fluid salts for 3 months, and sent the patient home, for $243. In 1972, when the government began to pay all expenses for patients with end-stage renal disease, nobody was interested anymore in inexpensive dialysis. Realizing that poor and developing countries cannot pay for commercial fluids for peritoneal dialysis, I came up with a system for peritoneal dialysis using two kettles. It was presented at the 2002 Nephrology Seminar in Bamberg and published by Dr. W. Schultz. 1 One way to get dialysis started in poor countries would be for dialysis patient associations in rich countries to adopt a poor country. They would find one dialysis patient originally from the poor country who is now in the United States. They would offer the patient a 6 week vacation in his or her native country provided that he or she would teach the two-kettle dialysis system to kidney patients in that country. So far, I have had no takers.

Récupéré en direct depuis OpenAlex et désinversé. Les résumés ne sont pas conservés dans cette base de données : les index inversés représentent 8,6 Go des 9,3 Go de texte de la base, et le serveur dispose de 13 Go libres.

Comment cette classification a été obtenuedéplier

Prédiction distillée sur la base complète

Imitation des enseignants

Ni prévalence calibrée, ni vérité terrain. Validation humaine à venir. Apprise à partir de 10 348 étiquettes directes de Codex et de 10 348 étiquettes directes de Gemma. Le mode candidate est l'union des têtes enseignantes seuillées; le consensus est leur intersection. Ces sorties portent le statut machine_predicted_unvalidated et ne sont ni des étiquettes humaines ni des étiquettes directes de modèles de pointe.

score de la tête « metaresearch » (Codex)0,000
score de la tête « metaresearch » (Gemma)0,000
Version: codex-gemma-dda1882f352aStatut de validation: machine_predicted_unvalidated
Catégories candidatesaucune
Catégories consensuellesaucune
DomaineSignal candidat: aucune · Signal consensuel: aucune
Devis d'étudeSignal candidat: Expérimental (laboratoire) · Signal consensuel: aucune
GenreSignal candidat: Empirique · Signal consensuel: Empirique
Score de désaccord entre enseignants0,397
Score d'incertitude au seuil0,487

Scores Codex et Gemma par catégorie

CatégorieCodexGemma
Métarecherche0,0000,000
Méta-épidémiologie (sens strict)0,0000,000
Méta-épidémiologie (sens large)0,0000,000
Bibliométrie0,0000,000
Études des sciences et des technologies0,0000,000
Communication savante0,0000,000
Science ouverte0,0000,000
Intégrité de la recherche0,0000,000
Charge utile insuffisante (le modèle a refusé de juger)0,0000,000

Scores machine (provisoires)

Les deux têtes enseignantes du modèle étudiant, lues sur ce travail. Un score ordonne la base pour la relecture; il n'affirme jamais une catégorie, et le statut de validation accompagne chaque rangée tel quel.

Scores de référence d'un modèle non mature (critères de maturité non atteints, 7 itérations). Un score ordonne; il n'affirme jamais une catégorie.

Tête enseignante Opus0,027
Tête enseignante GPT0,300
Écart entre enseignants0,273 · la distance entre les deux têtes enseignantes sur ce seul travail
Statut de validationscore_only:v0-immature-baseline · tel quel depuis la passe de notation : score_only signifie que le nombre peut ordonner les travaux, et qu'aucune étiquette de catégorie n'en découle

Classification

machine, non validée

Prédiction automatique; un appel candidat d’une seule tête enseignante, pas un consensus.

Les modèles n’ont appliqué aucune catégorie : rien dans la taxonomie ne correspondait à ce travail.
Devis d'étudeExpérimental (laboratoire)
Domainenon disponible
GenreEmpirique

Le détail, modèle par modèle et score par score, se trouve en fin de page sous « Comment cette classification a été obtenue ».

En bref

Citations0
Publié2003
Routes d'admission1
Résumé présentoui

Explorer davantage

Même revueASAIO JournalMême sujetOrgan Donation and TransplantationTravaux en français237 207